[Title 40 CFR 721.3180]
[Code of Federal Regulations (annual edition) - July 1, 1999 Edition]
[Title 40 - PROTECTION OF ENVIRONMENT]
[Chapter I - ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)]
[Subchapter R - TOXIC SUBSTANCES CONTROL ACT]
[Part 721 - SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES]
[Subpart E - Significant New Uses for Specific Chemical Substances]
[Sec. 721.3180 - Ethane, 2-chloro-1,1,1,2- tetrafluoro-.]
[From the U.S. Government Printing Office]
40PROTECTION OF ENVIRONMENT231999-07-011999-07-01falseEthane, 2-chloro-1,1,1,2- tetrafluoro-.721.3180Sec. 721.3180PROTECTION OF ENVIRONMENTENVIRONMENTAL PROTECTION AGENCY (CONTINUED)TOXIC SUBSTANCES CONTROL ACTSIGNIFICANT NEW USES OF CHEMICAL SUBSTANCESSignificant New Uses for Specific Chemical Substances
Sec. 721.3180 Ethane, 2-chloro-1,1,1,2- tetrafluoro-.
(a) Chemical substances and significant new uses subject to
reporting. (1) The chemical substance identified as ethane, 2-chloro-
1,1,1,2-tetrafluoro- (CAS number 2837-89-0) (PMN P-88-1763) is subject
to reporting under this section for the significant new uses described
in paragraph (a)(2) of this section.
(2) The significant new uses are:
(i) Hazard communication program. Requirements as specified in
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 1.0 percent;
concentration is set at 0.1 percent if new information requires a hazard
statement on the MSDS for cancer pursuant to Sec. 721.72(c)(5)), (f),
and (g)(5). The following additional human hazard precautionary
statement shall appear on the MSDS as specified in Sec. 721.72(c):
Inhalation of high concentrations of vapor is harmful and may cause
heart irregularities, unconsciousness, or death. Intentional misuse can
be fatal. Vapor reduces oxygen available for breathing and is heavier
than air. Liquid contact causes frostbite. The effects in animals from
single exposure by inhalation include central nervous system effects,
anesthesia, and decreased blood pressure. Cardiac sensitization occurred
in dogs exposed to a concentration of 2.5 percent in air and given an
intravenous epinephrine challenge. Repeated exposures produced increased
liver weights, anesthetic effects, irregular respiration, poor
coordination, and nonspecific effects such as decreased body weight
gain. However, no irreversible effects were seen as evidenced by
histopathologic evaluation. As part of an extensive toxicology program,
halogenated chlorofluorocarbon-124 will be tested in subchronic,
developmental, and chronic/cancer studies. Avoid breathing high
concentration of vapor. Use with sufficient ventilation to keep employee
exposure below recommended
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limits. Avoid contact of liquid with skin and eyes. Wear chemical splash
goggles and lined butyl gloves. Do NOT allow product to contact open
flame or electrical heating elements because dangerous decomposition
products may form.
The following additional human health hazard precautionary statements
shall appear on each label as specified in Sec. 721.72(b):
Inhalation of high concentrations of this substance in vapor form
may cause:
(a) Heart irregularities.
(b) Unconsciousness.
(c) Death.
(ii) Industrial, commercial, and consumer activities. Requirements
as specified in Sec. 721.80(q). In addition it is a significant new use
to use this substance as a blowing agent in the manufacture of
structural insulation foams for commercial or consumer purposes or to
use for commercial or consumer purposes structural insulation foams made
using this substance.
(b) Specific requirements. The provisions of subpart A of this part
apply to this section except as modified by this paragraph.
(1) Processors of this substance are not subject to this section if
they only service, repair, maintain, or sell products that contain the
substance.
(2) Notwithstanding Sec. 721.45(f), importers of structural
insulation foams made using this substance are subject to notification
requirements.
(3) Recordkeeping requirements. The following recordkeeping
requirements are applicable to manufacturers, importers, and processors
of this substance: Sec. 721.125 (a), (b), (c), and (f) through (i).
(4) Limitations or revocation of certain notification requirements.
The provisions of Sec. 721.185 apply to this section.
(5) Determining whether a specific use is subject to this section.
The provisions of Sec. 721.1725(b)(1) apply to this section.
[57 FR 32446, July 22, 1992, as amended at 58 FR 34204, June 23, 1993]