[Federal Register Volume 65, Number 114 (Tuesday, June 13, 2000)]
[Notices]
[Pages 37149-37153]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-14831]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[Program Announcement 01007]
Grants for Injury Control Research Centers; Notice of
Availability of Funds
A. Purpose
The Centers for Disease Control and Prevention (CDC) announces the
availability of fiscal year (FY) 2001 funds for Injury Control Research
Center (ICRC) grants. This program addresses the ``Healthy People
2010'' priority areas of Injury Prevention, Unintentional Injury
Prevention, and Violence and Abuse Prevention. For the conference copy
of ``Healthy People 2010,'' visit the Internet site: http://www.health.gov/healthypeople.
The purposes of this program are:
1. To support injury prevention and control research on priority
issues as delineated in: Healthy People 2010; Injury Control in the
1990's: A National Plan for Action; Reducing the Burden of Injury:
Advancing Prevention and Treatment; Injury in America; Injury
Prevention: Meeting the Challenge; Cost of Injury: A Report to the
Congress; and any list of research priorities published by the National
Center for Injury Prevention and Control (NCIPC);
2. To integrate, in the context of a national program, the
disciplines of engineering, epidemiology, medicine, biostatistics,
public health, law and criminal justice, and behavioral and social
sciences in order to prevent and control injuries more effectively;
3. To support the identification and description of injury
problems, to identify risk and protective factors that can be used to
design and test injury prevention and control strategies, to evaluate
current and new interventions for the prevention and control of
injuries, and to support the implementation of effective prevention and
control strategies in the public and private sector; and
4. To provide technical assistance to injury prevention and control
programs within a geographic region.
B. Eligible Applicants
This announcement will provide funding for applicants in regions
which do not have funded Injury Control Research Centers (ICRCs) and
for applicants in regions which have funded centers which must re-
compete for funding.
Eligible applicants include all nonprofit and for-profit
organizations in
[[Page 37150]]
Regions 1, 2, 5, 6, 7, 8, and 9. Thus, universities, colleges, research
institutions, hospitals, other public and private organizations, State
and local health departments, and small, minority and/or women-owned
businesses are eligible for these grants. Non-academic applicant
institutions should provide evidence of a collaborative relationship
with an academic institution.
Eligible applicants are limited to organizations in Region 1
(Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and
Vermont), Region 2 (New Jersey, New York, Puerto Rico, and Virgin
Islands), Region 5 (Illinois, Indiana, Michigan, Minnesota, Ohio, and
Wisconsin), Region 6 (Arkansas, Louisiana, New Mexico, Oklahoma, and
Texas), Region 7 (Iowa, Kansas, Missouri, and Nebraska), Region 8
(Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming), and
Region 9 (Arizona, California, Hawaii, Nevada, American Samoa, Guam,
Mariana Islands, Marshall Islands, Micronesia, and Palau).
Note:
ICRC grant awards are made to the applicant institution/
organization, not the Principal Investigator.
Note:
Public Law 104-65 states that an organization described in
section 501(c)(4) of the Internal Revenue Code of 1986 that engages
in lobbying activities is not eligible to receive Federal funds
constituting an award, grant, cooperative agreement, contract, loan,
or any other form.
C. Availability of Funds
Approximately $3,622,000 is expected to be available in FY 2001 to
fund approximately four awards. It is expected that the average award
will be $905,500 (total of direct and indirect costs). It is expected
that the awards will begin on or around September 1, 2001, and will be
made for a 12 month budget period within a project period of up to five
years. Applications that exceed the funding cap of $905,500 will be
excluded from the competition and returned to the applicant. Funding
estimates may change. Continuation awards within an approved project
period will be made on the basis of satisfactory progress as evidenced
by required reports and the availability of funds.
Use of Funds
Center funding is to be designated for two types of activities. One
type of activity is considered ``Core'' and includes administration,
management, general support services (e.g. statistical, library, media
relations, and advocacy) as well as activities associated with research
development, technical assistance, and education (e.g. seed projects,
training activities, and collaborative and technical assistance
activities with other groups). Funds may be allocated for trainee
stipends, tuition remission, and trainee travel, in accordance with the
current rates for the Public Health agencies. Indirect costs for these
trainee-related activities are limited to 8.0 percent. Defined research
projects constitute the second type of activity, and ICRCs are
encouraged to work toward addressing the breadth of the field. Core
activities and defined research projects may each constitute between 25
percent-75 percent of the operating budget and should be balanced in
such a way that the ICRC demonstrates productivity in research as well
as teaching and service. Applicants with less demonstrated expertise in
research are encouraged to devote a larger percentage of funds to
defined research projects in order to establish their capability as
research centers of excellence.
Grant funds will not be made available to support the provision of
direct care. Studies may be supported which evaluate methods of care
and rehabilitation for potential reductions in injury effects and
costs. Studies can be supported which identify the effect on injury
outcomes and cost of systems for pre-hospital, hospital, and
rehabilitative care and independent living.
Eligible applicants may enter into contracts, including consortia
agreements (as set forth in the PHS Grants Policy Statement, dated
April 1, 1994), as necessary to meet the requirements of the program
and strengthen the overall application.
Funding Preferences
Funding preference will be given to re-competing ICRCs. These
centers represent a long term investment for NCIPC and an established
resource for Injury Control related issues for their States and
regions.
D. Program Requirements
The following are applicant requirements:
1. Applicants must demonstrate expertise and conduct research
projects in at least one of the three phases of injury control
(prevention, acute care, or rehabilitation) and are encouraged to be
comprehensive.
2. Applicants must document ongoing injury-related research
projects or control activities currently supported by other sources of
funding.
3. Applicants must provide a director (Principal Investigator) who
has specific authority and responsibility to carry out the project. The
director must report to an appropriate institutional official, e.g.,
dean of a school, vice president of a university, or commissioner of
health. The director must have no less than 30 percent effort devoted
solely to this project with an anticipated range of 30 percent--50
percent.
4. Applicants must demonstrate experience in successfully
conducting, evaluating, and publishing injury research and/or
designing, implementing, and evaluating injury control programs.
5. Applicants must provide evidence of working relationships with
outside agencies and other entities which will allow for implementation
of any proposed intervention activities.
6. Applicants must provide evidence of involvement of specialists
or experts in medicine, engineering, epidemiology, law and criminal
justice, behavioral and social sciences, biostatistics, and/or public
health as needed to complete the plans of the center. These are
considered the disciplines and fields for ICRCs. An ICRC is encouraged
to involve biomechanicists in its research. This, again, may be
achieved through collaborative relationships as it is not a requirement
that all ICRCs have biomechanical engineering expertise.
7. Applicants must have established curricula and graduate training
programs in disciplines relevant to injury control (e.g., epidemiology,
biomechanics, safety engineering, traffic safety, behavioral sciences,
or economics).
8. Applicants must demonstrate the ability to disseminate injury
control research findings, translate them into interventions, and
evaluate their effectiveness.
9. Applicants must have an established relationship, demonstrated
by letters of agreement, with injury prevention and control programs or
injury surveillance programs being carried out in the region in which
the ICRC is located. Cooperation with private-sector programs, e.g.
``Safe USA'' partnerships, is encouraged.
10. Applicants should have an established or documented planned
relationship with organizations or individual leaders in communities
where injuries occur at high rates, e.g., minority communities.
E. Application Content
Use the information in the Program Requirements, Other
Requirements, and Evaluation Criteria sections to develop the
application content. Applications should include the following
information:
1. Face page
2. Description (abstract) and personnel
[[Page 37151]]
3. Table of contents
4. Detailed budget for the initial budget period: The budget should
reflect the composite figures for the grant. In addition, separate
budgets (direct and indirect costs) and justifications should be
provided for the following categories of activities:
a. Core activities, including management and administrative
functions, other non-research activities (e.g. education/training,
consultation, technical assistance, translation/dissemination, program
and policy development and evaluation, advocacy, and media activities,
etc.), and small seed projects of less than $15,000 for a one year
period or less.
b. Research Studies:
(1) Small studies of $15,000-75,000 for each, of one to three years
duration. These projects might be expansions of seed projects, either
further developing methods or hypotheses in preparation for a larger
investigation leading to the submission of an RO1 level proposal, or
may be stand-alone investigations sufficient to yield results worthy of
publication in a peer-reviewed journal and/or a technical report for a
legislative body, governmental agency, or injury control program.
(2) Larger scale studies with annual budgets exceeding $75,000 and
lasting up to five years. These projects typically will test hypotheses
and employ more sophisticated methodologies and/or larger sample sizes
than small studies.
For seed projects, only modest descriptions are required within the
application and/or clear definition of procedures used to select the
projects. More detailed descriptions, commensurate with costs, are
required for both small studies and larger scale projects.
5. Budget for entire proposed project period including budgets
pertaining to consortium/contractual arrangements.
6. Biographical sketches of key personnel, consultants, and
collaborators, beginning with the Principal Investigator and core
faculty.
7. Other support: This listing should include all other funds or
resources pending or currently available. For each grant or contract
include source of funds, amount of funding (indicate whether pending or
current), date of funding (initiation and termination), and
relationship to the proposed program.
8. Resources and environment.
9. Research plan:
a. ICRCs are to develop a range of research and other non-research
activities that are designed to advance the field of injury control
through development of new scientific or surveillance methods, creation
of new knowledge, and translation of knowledge into training, program
and policy development and evaluation activities or other applications
that will ultimately reduce injuries or their effects. ICRC
applications should articulate how the activities of their program are
integrated with each other so as to demonstrate the whole of the ICRCs
activities and their potential impact.
b. A detailed research plan (design and methods) including
hypothesis and expected outcome, value to field, and specific,
measurable, and time-framed objectives consistent with the activities
for each project within the proposed grant.
(1) Seed projects require a short write up describing the injury
control context of the study, the objective, the design, the setting
and participants, the intervention being addressed, main outcome
measurements, expected results, time lines, cost (direct and indirect),
and plans for translation/dissemination, and/or clear definition of
procedures used to select the projects.
(2) Small research projects require a 10-15 page write up
describing the accomplishment of all the steps, including the
development and testing of methods, the instruments, and the collection
of preliminary data, needed to take an innovative approach and develop
it to the level of a larger investigation leading to the submission of
an RO1 level proposal or a stand-alone investigation sufficient to
yield results worthy of publication in a peer-reviewed journal and/or a
technical report for a legislative body, governmental agency, or injury
control program.
(3) Large research projects require an RO1 level write up as
described in the PHS 398 (Rev. 4/98) guidelines and should be included
as appendices of the application.
(4) A detailed evaluation plan which should address outcome and
cost-effectiveness evaluations as well as formative, efficacy, and
process evaluation.
Include in the narrative for each small research project and large
project in the research plan section of the application:
(1) Title of Project
(2) Project Director/Lead Investigator
(3) Institution(s)
(4) Categorization as to ``Prevention, Acute Care, Rehabilitation,
or Biomechanics''
(5) Categorization as to ``Seed Project, Small Project, or Large
Project''
(6) Categorization as to ``New or Ongoing Project''
(7) Cost/Year (Direct and Indirect)
(8) Research Training? Names, Degrees of Persons Trained or in
Training
(9) Key Words
(10) Brief Summary of Project including Intended Application of
Finding (Abstract)
c. A description of the core faculty and its role in implementing
and evaluating the proposed programs. The applicant should clearly
specify how disciplines will be integrated to achieve the ICRCs
objectives.
d. Charts showing the proposed organizational structure of the ICRC
and its relationship to the broader institution of which it is a part,
and, where applicable, to affiliate institutions or collaborating
organizations. These charts should clearly detail the lines of
authority as they relate to the center or the project, both
structurally and operationally. ICRC directors should report to an
appropriate organizational level (e.g. dean of a school, vice president
of a university, or commissioner of health), demonstrating strong
institution-wide support of ICRC activities and ensuring oversight of
the process of interdisciplinary activity.
e. Documentation of the involved public health agencies and other
public and private sector entities to be involved in the proposed
program, including letters that detail commitments of support and a
clear statement of the role, activities, and participating personnel of
each agency or entity.
An applicant organization has the option of having specific salary
and fringe benefit amounts for individuals omitted from the copies of
the application which are made available to outside reviewing groups.
To exercise this option: on the original and five copies of the
application, the applicant must use asterisks to indicate those
individuals for whom salaries and fringe benefits are not shown; the
subtotals must still be shown. In addition, the applicant must submit
an additional copy of page four of Form PHS-398, completed in full,
with the asterisks replaced by the salaries and fringe benefits. This
budget page will be reserved for internal staff use only.
F. Submission and Deadline
Submit the original and five copies of PHS 398 (OMB Number 0925-
0001)and adhere to the instructions on the Errata Instruction sheet for
PHS 398). Forms are in the application kit.
On or before November 1, 2000, submit the application to the Grants
Management Specialist identified in the Where to Obtain Additional
Information section of this announcement.
[[Page 37152]]
Applications shall be considered as meeting the deadline if they
are either:
1. Received on or before the deadline date; or
2. Sent on or before the deadline date and received in time for
submission to the independent review group. Applicants must request a
legibly dated U.S. Postal Service postmark or obtain a legibly dated
receipt from a commercial carrier or the U.S. Postal Service. Private
metered postmarks shall not be acceptable as proof of timely mailing.
Late Applications: Applications which do not meet the criteria in
(1.) or (2.) above are considered late applications, will not be
considered, and will be returned to the applicant.
G. Evaluation Criteria
Upon receipt, applications will be reviewed by CDC staff for
completeness and responsiveness as outlined under the previous heading
Program Requirements. Incomplete applications and applications that are
not responsive will be returned to the applicant without further
consideration.
Applications which are complete and responsive may be subjected to
a preliminary evaluation (triage) by the Injury Research Grant Review
Committee (IRGRC) to determine if the application is of sufficient
technical and scientific merit to warrant further review by the IRGRC.
CDC will withdraw from further consideration applications judged to be
noncompetitive and promptly notify the principal investigator/program
director and the official signing for the applicant organization. Those
applications judged to be competitive will be further evaluated by a
dual review process.
Awards will be made based on priority scores assigned to
applications by the IRGRC, programmatic priorities and needs determined
by a secondary review committee (the Advisory Committee for Injury
Prevention and Control), and the availability of funds.
1. Review by the Injury Research Grants Review Committee (IRGRC)
Initial peer review of ICRC grant applications will be conducted by
the IRGRC, which will recommend the application for further
consideration or not for further consideration. For those applications
recommended for further consideration, a team of peer reviewers,
including members of the IRGRC, will conduct on-site visits at each
applicant institution, generate summary statements for the visits, and
report its assessment to the IRGRC.
Factors to be considered by the IRGRC include:
a. The specific aims of the application, e.g., the long-term
objectives and intended accomplishments. Approval of research projects
(including new research projects proposed during the five year funding
cycle) is subject to peer review.
(1) Seed projects will be evaluated collectively on the mechanism
for solicitation of projects, on the technical/scientific merit review,
and on the selection and monitoring of projects.
(2) Small projects will be evaluated individually on the innovative
approach and proposed methods for achieving an investigation sufficient
to support a submission of an RO1 level proposal and/or worthy of
publication in a peer-reviewed journal and/or a technical report for a
legislative body, governmental agency, or injury control program.
(3) Large projects will be evaluated individually according to
existing RO1 level project standards as described in the PHS 398 (Rev.
4/98) guidelines. An application must have a minimum of three large
research projects approved in order to be recommended for further
consideration.
b. The scientific and technical merit of the overall application,
including the significance and originality (e.g., new topic, new
method, new approach in a new population, or advancing understanding of
the problem) of the proposed research.
c. The extent to which the evaluation plan will allow for the
measurement of progress toward the achievement of stated application
objectives.
d. Qualifications, adequacy, and appropriateness of personnel to
accomplish the proposed activities.
e. The soundness of the proposed budget in terms of adequacy of
resources and their allocation.
f. In addition to conducting defined research projects, ICRCs are
expected to devote substantial attention to activities directed at
advancing the field through other activities that are designed to
improve research capabilities and translate research into practice.
Examples of such activities include consultation and technical
assistance that are responsive to regional and state priorities,
professional training for researchers and practitioners, program
development, and evaluation endeavors. The degree of effort devoted to
these aspects of an ICRCs program should be clearly stated in the
justification and the budget. The degree of effort may be varied and
should reflect the specific focus and goals of the ICRC.
g. Details of progress in the most recent funding period should be
provided in the application if the applicant is submitting a re-
competing application. Documented examples of success include:
development of pilot projects; completion of high quality research
projects; publication of findings in peer reviewed scientific and
technical journals; number of professionals trained; ongoing provision
of consultation and technical assistance; integration of disciplines;
translation of research into implementation; impact on injury control
outcomes including legislation, regulation, treatment, and behavior
modification interventions.
h. Does the application adequately address the requirements of
Title 45 CFR Part 46 for the protection of human subjects?
i. Does the applicant meet the CDC Policy requirements regarding
the inclusion of women, ethnic, and racial groups in the proposed
research?
j. Does the application adequately address the requirements of the
``PHS Policy on Humane Care and Use of Laboratory Animals by Awardee
Institutions?'
2. Review by the CDC Advisory Committee for Injury Prevention and
Control (ACIPC)
Secondary review of ICRC grant applications will be conducted by
the Science and Program Review Work Group (SPRWG) of the ACIPC. The
SPRWG consists of ACIPC members, Federal ex officio participants, and
organizational liaisons. The Federal ex officio participants will be
responsible for identifying proposals in overlapping areas of research
interest so that unwarranted duplication in federally-funded research
can be avoided. The NCIPC Division Associate Directors for Science
(ADS) or their designees will address the SPRWG to assure that research
priorities of the announcement are understood and to provide background
regarding current research activities. These recommendations will be
presented to the entire ACIPC in the form of a report by the Chairman
of the SPRWG. The ACIPC will vote to approve, disapprove, or modify
these recommendations for funding consideration.
These recommendations, based on the results of the review by the
IRGRC, the relevance and balance of the proposed research relative to
the NCIPC programs and priorities, and the assurance of no duplication
of federally-funded research, are presented to the Director, NCIPC, for
funding decisions.
Factors to be considered by the ACIPC include:
a. The results of the peer review.
b. The significance of the proposed activities as they relate to
national
[[Page 37153]]
program priorities, geographic balance, and the achievement of national
objectives.
c. The overall balance of the ICRC program in addressing the three
phases of injury control (prevention, acute care, and rehabilitation);
the control of injury among populations who are at increased risk,
including racial/ethnic minority groups, the elderly and children; the
major causes of intentional and unintentional injury; and the major
disciplines of injury control (such as biomechanics, epidemiology, and
behavioral science).
d. Budgetary considerations. The ACIPC will recommend annual
funding levels as detailed under the heading, Availability of Funds.
3. Continued Funding
Continuation awards within the project period will be made on the
basis of the availability of funds and the following criteria:
a. The accomplishments of the current budget period show that the
applicant's objectives as prescribed in the yearly work plans are being
met;
b. The objectives for the new budget period are realistic,
specific, and measurable;
c. The methods described will clearly lead to achievement of these
objectives;
d. The evaluation plan allows management to monitor whether the
methods are effective by having clearly defined process, impact, and
outcome objectives, and the applicant demonstrates progress in
implementing the evaluation plan; and
e. The budget request is clearly explained, adequately justified,
reasonable, and consistent with the intended use of grant funds.
H. Other Requirements
Technical Reporting Requirements
Provide CDC with original plus two copies of
1. progress report annually;
2. financial status report, no more than 90 days after the end of
the budget period; and
3. final financial status report and performance report, no more
than 90 days after the end of the project period.
Send all reports to the Grants Management Specialist identified in
the Where to Obtain Additional Information section of this
announcement.
The following additional requirements are applicable to this
program. For a complete description of each see Addendum 1 in the
application kit.
AR-1 Human Subjects Certification
AR-2 Requirements for inclusion of Women and Racial and Ethnic
Minorities in Research
AR-3 Animal Subjects Requirements
AR-9 Paperwork Reduction Act Requirements
AR-10 Smoke-Free Workplace Requirement
AR-11 Healthy People 2010
AR-12 Lobbying Restrictions
AR-13 Prohibition on Use of CDC funds for Certain Gun Control
Activities
AR-20 Conference Activities within Grants/Cooperative Agreements
I. Authority and Catalog of Federal Domestic Assistance Number
This program is authorized under Sections 301, 391, 392, 393, and
394 of the Public Health Service Act, [42 U.S.C. 241, 280b, 280b-1,
280b-1a, and 280b-2] as amended. Catalog of Federal Domestic Assistance
number is 93.136.
J. Where To Obtain Additional Information
For this announcement and other CDC announcements, see the CDC home
page on the Internet: http://www.cdc.gov.
To receive additional written information and to request an
application kit, call 1-888-GRANTS4 (1-888-472-6874). You will be asked
to leave your name and address and will be instructed to identify the
Announcement number of interest. A complete program description and
information on application procedures are contained in the application
package.
If you have questions after reviewing the contents of all the
documents, business management assistance may be obtained from: Joanne
Wojcik, Grants Management Specialist, Grants Management Branch,
Procurement and Grants Office, Centers for Disease Control and
Prevention (CDC), Colgate Building, Room 3000, 2920 Brandywine Road,
Atlanta, GA 30341-4146, Telephone 770-488-2717, Internet address:
[email protected]
Programmatic assistance may be obtained from: Tom Voglesonger,
Program Manager, Office of Research Grants, National Center for Injury
Prevention and Control, Centers for Disease Control and Prevention
(CDC), 4770 Buford Highway, NE., (K58), Atlanta, GA 30341-3724,
Telephone 770-488-4265, Internet address: [email protected].
Please refer to Announcement 01007 when requesting information and
submitting an application.
Dated: June 7, 2000.
Henry S. Cassell, III,
Acting Director, Procurement and Grants Office, Centers for Disease
Control and Prevention (CDC).
[FR Doc. 00-14831 Filed 6-12-00; 8:45 am]
BILLING CODE 4163-18-P