[Federal Register Volume 65, Number 244 (Tuesday, December 19, 2000)]
[Notices]
[Page 79374]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-32221]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health/National Institute of Environmental 
Health Sciences


Submission for OMB Review; Comment Request; Environmental Factors 
in the Development of Polycystic Ovary Syndrome

SUMMARY: Under the provisions of section 3507(a)(1)(D) of the Paperwork 
Reduction Act of 1995, the National Institute of Environmental Health 
Sciences (NIEHS), the National Institutes of Health (NIH) has submitted 
to the Office of Management and Budget (OMB) a request for review and 
approval of the information collection listed below. This proposed 
information collection was previously published in the Federal Register 
on September 1, 2000, page 53326 and allowed 60-days for public 
comment. No public comments were received. The purpose of this notice 
is to allow an additional 30 days for public comment. The National 
Institutes of Health may not conduct or sponsor, and the respondent is 
not required to, an information collection that has been extended, 
revised, or implemented on or after October 1, 1995, unless it displays 
a currently valid OMB control number.

Proposed Collection

    Title: Environmental Factors in the Development of Polycystic Ovary 
Syndrome. Type of Information Collection Request: NEW. Need and Use of 
Information Collection: We will administer a brief telephone survey to 
2032 twin women from the Mid-Atlantic Twin Registry (MATR) who 
previously reported having irregular periods and/or cystic ovaries on a 
MATR General Health History Survey. Question in the proposed survey 
focus on the two hallmark features of Polycystic Ovary Syndrome (PCOS), 
hyperandrogenism and anovulation, other relevant physical 
characteristics, and if the woman has a living female twin sister. 
Women will also be asked for permission to recontact them for potential 
participation in future PCOS studies. The data will be used in 
statistical modeling analyses to identify those women with a high 
probability of having PCOS and estimate the number of potential 
candidates for future PCOS studies. Frequency of Response: One time. 
Affected Public: Individuals; Type of Respondents: Adult women. The 
annual reporting burden is as follows: Estimated Number of Respondents: 
2,100; Estimated Number of Responses per Respondent: 1; Average Burden 
Hours Per Response: 0.167; and Estimated Total Annual Burden Hours 
Requested: 350.7. The annualized cost to respondents is estimated at: 
$3,507.00. There are no Capital Costs to report. There are no Operating 
or Maintenance Costs to report.

Request for Comments

    Written comments and/or suggestions from the public and affected 
agencies are invited on one or more of the following points: (1) 
Whether the proposed collection of information is necessary for the 
proper performance of the function of the agency, including whether the 
information will have practical utility; (2) The accuracy of the 
agency's estimate of burden of the proposed collection of information, 
including the validity of the methodology and assumptions used; (3) 
Ways to enhance the quality, utility, and clarity of the information to 
be collected; and (4) Ways to minimize the burden of the collection of 
information on those who are to respond, including the use of 
appropriate automated, electronic, mechanical, or other technological 
collection techniques or other forms of information technology.

Direct Comments to OMB

    Written comment and/or suggestions regarding the item(s) contained 
in this notice, especially regarding the estimated public burden and 
associated response time, should be directed to the: Office of 
Management and Budget, Office of Regulatory Affairs, New Executive 
Office Building, Room 10235, Washington, DC. 20503, Attention: Desk 
Officer for NIH. To request more information on the proposed project or 
to obtain a copy of the data collection plans and instruments, contact 
Dr. Patricia C. Chulada, Clinical Research Scientist, Clinical Research 
Office, NIEHS, P.O. Box 12233, Research Triangle Park, NC 27709 or call 
non-toll-free number (919) 541-7736 or E-mail your request, including 
your address to: [email protected].

DATES: Comments Due Date: Comments regarding this information 
collection are best assured of having their full effect if received on 
or before January 18, 2001.

    Dated: December 7, 2000.
Francine Little,
Associate Director for Management, NIEHS.
[FR Doc. 00-32221 Filed 12-18-00; 8:45 am]
BILLING CODE 4140-01-M