[Federal Register Volume 70, Number 28 (Friday, February 11, 2005)]
[Notices]
[Pages 7364-7377]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 05-2714]
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Part IV
Environmental Protection Agency
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Fifty-Fifth Report of the TSCA Interagency Testing Committee to the
Administrator of the Environmental Protection Agency; Receipt of Report
and Request for Comments; Notice
Federal Register / Vol. 70, No. 28 / Friday, February 11, 2005 /
Notices
[[Page 7364]]
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ENVIRONMENTAL PROTECTION AGENCY
[OPPT-2004-0130; FRL-7692-1]
Fifty-Fifth Report of the TSCA Interagency Testing Committee to
the Administrator of the Environmental Protection Agency; Receipt of
Report and Request for Comments
AGENCY: Environmental Protection Agency (EPA).
ACTION: Notice.
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SUMMARY: The Toxic Substances Control Act (TSCA) Interagency Testing
Committee (ITC) transmitted its Fifty-Fifth Report to the Administrator
of EPA on December 8, 2004. In the 55\th\ ITC Report, which is included
with this notice, the ITC is revising the Priority Testing List by
adding a category of high production volume (HPV) orphan chemicals and
requesting that EPA add these chemicals to the TSCA section 8(a)
Preliminary Assessment Information Reporting (PAIR) rule and the TSCA
section 8(d) Health and Safety Data Reporting (HaSDR) rule. The ITC is
also removing the following chemicals from the Priority Testing List:
3-amino-5-mercapto-1,2,4-triazole; glycoluril; benzenamine, 3-chloro-
2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-; stannane,
dimethylbis[(1-oxoneodecyl)oxy]-; benzene, 1,3,5-tribromo-2-(2-
propenyloxy)-; and1-triazene, 1,3-diphenyl-.]. Since the 55\th\ Report
was ITC transmitted to the Administrator and made publicly available on
http://www.epa.gov/opptintr/itc/, five HPV orphan chemicals have been
removed from the Priority Testing List because chemical manufacturers
committed to prepare robust summaries for these chemicals in response
to the HPV Challenge Program. The ITC encourages other manufacturers to
make similar commitments so their chemicals can be removed from the
Priority Testing List and potentially avoid being added to PAIR and
HaSDR rules.
DATES: Comments, identified by docket identification (ID) number OPPT-
2004-0130, must be received on or before March 14, 2005.
ADDRESSES: Comments may be submitted electronically, by mail, or
through hand delivery/courier. Follow the detailed instructions as
provided in Unit I. of the SUPPLEMENTARY INFORMATION.
FOR FURTHER INFORMATION CONTACT: For general information contact:
Colby Lintner, Regulatory Coordinator, Environmental Assistance
Division (7408M), Office of Pollution Prevention and Toxics,
Environmental Protection Agency, 1200 Pennsylvania Ave., NW.,
Washington, DC 20460-0001; telephone number: (202) 554-1404; e-mail
address: TSCA-H[email protected].
For technical information contact: John D. Walker, Director, TSCA
Interagency Testing Committee (7401), Office of Pollution Prevention
and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave.,
NW., Washington, DC 20460-0001; e-mail address: [email protected].
SUPPLEMENTARY INFORMATION:
I. General Information
A. Does this Action Apply to Me?
This notice is directed to the public in general. It may, however,
be of particular interest to you if you manufacture (defined by statute
to include import) and/or process TSCA-covered chemicals and you may be
identified by the North American Industrial Classification System
(NAICS) codes 325 and 32411. Because this notice is directed to the
general public and other entities may also be interested, the Agency
has not attempted to describe all the specific entities that may be
interested in this action. If you have any questions regarding the
applicability of this action to a particular entity, consult the
technical person listed under FOR FURTHER INFORMATION CONTACT.
B. How Can I Get Copies of this Document and Other Related Information?
1. Docket. EPA has established an official public docket for this
action under docket ID number OPPT-2004-0130. The official public
docket consists of the documents specifically referenced in this
action, any public comments received, and other information related to
this action. Although a part of the official docket, the public docket
does not include Confidential Business Information (CBI) or other
information whose disclosure is restricted by statute. The official
public docket is the collection of materials that is available for
public viewing at the EPA Docket Center, Rm. B102-Reading Room, EPA
West, 1301 Constitution Ave., NW., Washington, DC. The EPA Docket
Center is open from 8:30 a.m. to 4:30 p.m., Monday through Friday,
excluding legal holidays. The EPA Docket Center Reading Room telephone
number is (202) 566-1744 and the telephone number for the OPPT Docket,
which is located in EPA Docket Center, is (202) 566-0280.
2. Electronic access. You may access this Federal Register document
electronically through the EPA Internet under the ``Federal Register''
listings at http://www.epa.gov/fedrgstr/. You may also access
additional information about the ITC at http://www.epa.gov/opptintr/
itc/ or through the web site for the Office of Prevention, Pesticides
and Toxic Substances (OPPTS) at http://www.epa.gov/opptsfrs/home/
opptsim.htm/.
An electronic version of the public docket is available through
EPA's electronic public docket and comment system, EPA Dockets. You may
use EPA Dockets at http://www.epa.gov/edocket/ to submit or view public
comments, access the index listing of the contents of the official
public docket, and to access those documents in the public docket that
are available electronically. Although not all docket materials may be
available electronically, you may still access any of the publicly
available docket materials through the docket facility identified in
Unit I.B.1. Once in the system, select ``search,'' then key in the
appropriate docket ID number.
Certain types of information will not be placed in the EPA Dockets.
Information claimed as CBI and other information whose disclosure is
restricted by statute, which is not included in the official public
docket, will not be available for public viewing in EPA's electronic
public docket. EPA's policy is that copyrighted material will not be
placed in EPA's electronic public docket but will be available only in
printed, paper form in the official public docket. To the extent
feasible, publicly available docket materials will be made available in
EPA's electronic public docket. When a document is selected from the
index list in EPA Dockets, the system will identify whether the
document is available for viewing in EPA's electronic public docket.
Although not all docket materials may be available electronically, you
may still access any of the publicly available docket materials through
the docket facility identified in Unit I.B.1. EPA intends to work
towards providing electronic access to all of the publicly available
docket materials through EPA's electronic public docket.
For public commenters, it is important to note that EPA's policy is
that public comments, whether submitted electronically or in paper,
will be made available for public viewing in EPA's electronic public
docket as EPA receives them and without change, unless the comment
contains copyrighted material, CBI, or other information whose
disclosure is restricted by statute. When EPA identifies a comment
containing copyrighted material, EPA will provide
[[Page 7365]]
a reference to that material in the version of the comment that is
placed in EPA's electronic public docket. The entire printed comment,
including the copyrighted material, will be available in the public
docket.
Public comments submitted on computer disks that are mailed or
delivered to the docket will be transferred to EPA's electronic public
docket. Public comments that are mailed or delivered to the docket will
be scanned and placed in EPA's electronic public docket. Where
practical, physical objects will be photographed, and the photograph
will be placed in EPA's electronic public docket along with a brief
description written by the docket staff.
C. How and to Whom Do I Submit Comments?
You may submit comments electronically, by mail, or through hand
delivery/courier. To ensure proper receipt by EPA, identify the
appropriate docket ID number in the subject line on the first page of
your comment. Please ensure that your comments are submitted within the
specified comment period. Comments received after the close of the
comment period will be marked ``late.'' EPA is not required to consider
these late comments. If you wish to submit CBI or information that is
otherwise protected by statute, please follow the instructions in Unit
I.D. Do not use EPA Dockets or e-mail to submit CBI or information
protected by statute.
1. Electronically. If you submit an electronic comment as
prescribed in this unit, EPA recommends that you include your name,
mailing address, and an e-mail address or other contact information in
the body of your comment. Also include this contact information on the
outside of any disk or CD ROM you submit, and in any cover letter
accompanying the disk or CD ROM. This ensures that you can be
identified as the submitter of the comment and allows EPA to contact
you in case EPA cannot read your comment due to technical difficulties
or needs further information on the substance of your comment. EPA's
policy is that EPA will not edit your comment, and any identifying or
contact information provided in the body of a comment will be included
as part of the comment that is placed in the official public docket,
and made available in EPA's electronic public docket. If EPA cannot
read your comment due to technical difficulties and cannot contact you
for clarification, EPA may not be able to consider your comment.
i. EPA Dockets. Your use of EPA's electronic public docket to
submit comments to EPA electronically is EPA's preferred method for
receiving comments. Go directly to EPA Dockets at http://www.epa.gov/
edocket/, and follow the online instructions for submitting comments.
Once in the system, select ``search,'' and then key in docket ID number
OPPT-2004-0130. The system is an `` anonymous access'' system, which
means EPA will not know your identity, e-mail address, or other contact
information unless you provide it in the body of your comment.
ii. E-mail. Comments may be sent by e-mail to [email protected],
Attention: Docket ID Number OPPT-2004-0130. In contrast to EPA's
electronic public docket, EPA's e-mail system is not an ``anonymous
access'' system. If you send an e-mail comment directly to the docket
without going through EPA's electronic public docket, EPA's e-mail
system automatically captures your e-mail address. E-mail addresses
that are automatically captured by EPA's e-mail system are included as
part of the comment that is placed in the official public docket, and
made available in EPA's electronic public docket.
iii. Disk or CD ROM. You may submit comments on a disk or CD ROM
that you mail to the mailing address identified in Unit I.C.2. These
electronic submissions will be accepted in WordPerfect or ASCII file
format. Avoid the use of special characters and any form of encryption.
2. By mail. Send your comments to: Document Control Office (7407M),
Office of Pollution Prevention and Toxics (OPPT), Environmental
Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-
0001.
3. By hand delivery or courier. Deliver your comments to: OPPT
Document Control Office (DCO), EPA East Bldg., Rm. 6428, 1201
Constitution Ave., NW., Washington, DC. Attention: Docket ID Number
OPPT-2004-0130. The DCO is open from 8 a.m. to 4 p.m., Monday through
Friday, excluding legal holidays. The telephone number for the DCO is
(202) 564-8930.
D. How Should I Submit CBI to the Agency?
Do not submit information that you consider to be CBI
electronically through EPA's electronic public docket or by e-mail. You
may claim information that you submit to EPA as CBI by marking any part
or all of that information as CBI (if you submit CBI on disk or CD ROM,
mark the outside of the disk or CD ROM as CBI and then identify
electronically within the disk or CD ROM the specific information that
is CBI). Information so marked will not be disclosed except in
accordance with procedures set forth in 40 CFR part 2.
In addition to one complete version of the comment that includes
any information claimed as CBI, a copy of the comment that does not
contain the information claimed as CBI must be submitted for inclusion
in the public docket and EPA's electronic public docket. If you submit
the copy that does not contain CBI on disk or CD ROM, mark the outside
of the disk or CD ROM clearly that it does not contain CBI. Information
not marked as CBI will be included in the public docket and EPA's
electronic public docket without prior notice. If you have any
questions about CBI or the procedures for claiming CBI, please consult
the technical person listed under FOR FURTHER INFORMATION CONTACT.
E. What Should I Consider as I Prepare My Comments for EPA?
We invite you to provide your views and comments on the ITC's
55\th\ Report. You may find the following suggestions helpful for
preparing your comments:
1. Explain your views as clearly as possible.
2. Describe any assumptions that you used.
3. Provide copies of any technical information and/or data you used
that support your views.
4. Provide specific examples to illustrate your concerns.
5. Make sure to submit your comments by the deadline in this
notice.
6. To ensure proper receipt by EPA, be sure to identify the docket
ID number assigned to this action in the subject line on the first page
of your response. You may also provide the name, date, and Federal
Register citation.
II. Background
The Toxic Substances Control Act (TSCA) (15 U.S.C. 260l et seq.)
authorizes the Administrator of the EPA to promulgate regulations under
section 4(a) of TSCA requiring testing of chemicals and chemical groups
in order to develop data relevant to determining the risks that such
chemicals and chemical groups may present to health or the environment.
Section 4(e) of TSCA established the ITC to recommend chemicals and
chemical groups to the Administrator of the EPA for priority testing
consideration. Section 4(e) of TSCA directs the ITC to revise the TSCA
section 4(e) Priority Testing List at least every 6 months.
A. The ITC's 55\th\ Report
The 55\th\ ITC Report was transmitted to EPA's Administrator on
December 8,
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2004, and is included in this notice. In the 55\th\ ITC Report, the ITC
is revising the Priority Testing List by adding a category of HPV
orphan chemicals and requesting that EPA add these chemicals to the
TSCA section 8(a) PAIR rule and the TSCA section 8(d) HaSDR rule. The
ITC is also removing the following chemicals from the Priority Testing
List: 3-amino-5-mercapto-1,2,4-triazole; glycoluril; benzenamine, 3-
chloro-2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-; stannane,
dimethylbis[(1-oxoneodecyl)oxy]-; benzene, 1,3,5-tribromo-2-(2-
propenyloxy)-; and 1-triazene, 1,3-diphenyl-.
B. Status of the Priority Testing List
The current TSCA 4(e) Priority Testing List as of December 2004 can
be found in Table 1 of the 55\th\ ITC Report, which is included in this
notice.
List of Subjects
Environmental protection, Chemicals, Hazardous substances.
Dated: February 3, 2005.
Charles M. Auer,
Director, Office of Pollution Prevention and Toxics.
Fifty-Fifth Report of the TSCA Interagency Testing Committee to the
Administrator, U.S. Environmental Protection Agency
Table of Contents
Summary
I. Background
II. TSCA Section 8 Reporting
A. TSCA Ssection 8 Reporting Rules
B. ITC's Use of TSCA Section 8 and Other Information
C. Previous Requests to Add Chemicals to the TSCA Section 8(a) PAIR
Rule
D. New Requests to Add Chemicals to the TSCA Section 8(a) PAIR and
8(d) HaSDR Rules
III. ITC's Activities During this Reporting Period (May to November
2004)
IV. Revisions to the TSCA Section 4(e) Priority Testing List
A. Chemicals Added to the Priority Testing List: HPV Orphan
Chemicals
B. Chemicals Removed From the Priority Testing List
1. 3-Amino-5-mercapto-1,2,4-triazole.
2. Glycoluril.
3. Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-4-
(trifluoromethyl)-.
4. Stannane, dimethylbis[(1-oxoneodecyl)oxy]-.
5. Benzene, 1,3,5-tribromo-2-(2-propenyloxy)-.
6. 1-Triazene, 1,3-diphenyl-.
V. References
VI. The TSCA Interagency Testing Committee
Summary
In this 55\th\ ITC Report, the ITC is revising the Priority
Testing List by adding a category of High Production Volume (HPV)
orphan chemicals and requesting that EPA add these chemicals to the
Toxic Substances Control Act (TSCA) section 8(a) Preliminary
Assessment Information Reporting (PAIR) rule and the TSCA section
8(d) Health and Safety Data Reporting (HaSDR) rule. The ITC is also
removing the following chemicals from the Priority Testing List: 3-
amino-5-mercapto-1,2,4-triazole; glycoluril; benzenamine, 3-chloro-
2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-; stannane,
dimethylbis[(1-oxoneodecyl)oxy]-; benzene, 1,3,5-tribromo-2-(2-
propenyloxy)-; and 1-triazene, 1,3-diphenyl-.
The TSCA section 4(e) Priority Testing List is Table 1 of this
unit.
Table 1.--The TSCA Section 4(e) Priority Testing List (November 2004)
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ITC Report Date Chemical name/group Action
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31 January 1993 13 Chemicals with Designated
insufficient dermal
absorption rate data
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I. Background
The ITC was established by section 4(e) of TSCA ``to make
recommendations to the Administrator respecting the chemical
substances and mixtures to which the Administrator should give
priority consideration for the promulgation of rules for testing
under section 4(a).... At least every six months ..., the Committee
shall make such revisions to the Priority Testing List as it
determines to be necessary and transmit them to the Administrator
together with the Committee's reasons for the revisions'' (Public
Law 94-469, 90 Stat. 2003 et seq., 15 U.S.C. 2601 et seq.). ITC
Reports are available from the ITC's web site (http://www.epa.gov/
opptintr/itc/) within a few days of submission to the Administrator
and from the EPA's web site http://www.epa.gov/fedrgstr/ after
publication in the Federal Register. The ITC produces its revisions
to the Priority Testing List with administrative and technical
support from the ITC Staff and ITC Members and their U.S. Government
organizations, and contract support provided by EPA. ITC Members and
Staff are listed at the end of this report.
II. TSCA Section 8 Reporting
A. TSCA Section 8 Reporting Rules
Following receipt of the ITC's Report (and the revised Priority
Testing List) by the EPA Administrator, the EPA's Office of
Pollution Prevention and Toxics (OPPT) may add the chemicals from
the revised Priority Testing List to the TSCA section 8(a)
Preliminary Assessment Information Reporting (PAIR) and TSCA section
8(d) Health and Safety Data Reporting (HaSDR) rules. The PAIR rule
requires producers and importers of chemicals added to the Priority
Testing List to submit production and exposure reports (http://
www.epa.gov/opptintr/chemtest/pairform.pdf/). The HaSDR rule
requires producers, importers and processors of all chemicals added
to the Priority Testing List to submit unpublished health and safety
studies under TSCA section 8(d) that must be in compliance with the
revised HaSDR rule (Ref. 1). All submissions must be received by the
EPA within 90 days of the reporting rules Federal Register
publication date.
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B. ITC's Use of TSCA Section 8 and Other Information
The ITC's use of TSCA section 8 and other information is
described in previous ITC Reports (http://www.epa.gov/opptintr/itc/
rptmain.htm/).
C. Previous Requests to Add Chemicals to the TSCA Section 8(a) PAIR
Rule
In its 53\rd\ Report, the ITC requested that EPA add 3
pyridinamines and 20 tungsten compounds to the TSCA section 8(a)
PAIR rule (Ref. 2). On December 7, 2004, EPA issued a final rule,
pursuant to TSCA section 8(a) requiring producers and importers of
these 23 chemicals to report production, importation, and exposure
data to EPA (Ref. 3).
D. New Requests to Add Chemicals to the TSCA Section 8(a) PAIR and
8(d) HaSDR Rules
In this report, the ITC is requesting that EPA add the HPV
orphan chemicals listed in Appendix A to the TSCA section 8(a) PAIR
and 8(d) HaSDR rules. The ITC is requesting that these HPV orphan
chemicals be added to the TSCA section 8(a) PAIR and 8(d) HaSDR
rules because no voluntary studies have been submitted to the EPA in
response to the HPV Challenge Program (http://www.epa.gov/opptintr/
chemrtk/volchall.htm/).
III. ITC's Activities During this Reporting Period (May to November
2004)
During this reporting period, the ITC reviewed the reports
submitted in response to the June 11, 2003, PAIR rule (Ref. 4) and
the May 4, 2004, TSCA section 8(d) HaSDR rule (Ref. 5). The ITC is
continuing to review these reports.
The ITC also met with EPA to discuss procedures for making data
publicly available on HPV orphan chemicals (HPV chemicals for which
no sponsors have volunteered to develop and submit robust summaries
to the EPA). The ITC's discussions with EPA are described in section
IV. of this report.
As noted in the 51\st\ and 54\th\ ITC Reports (Refs. 6 and 7),
the ITC continues to request the following information on vanadium
compounds:
1. Recent non-CBI estimates of annual production or importation
volume data and trends, and use information, including percentages
of production or importation that are associated with different
uses.
2. Estimates of the number of humans and concentrations of
vanadium chemicals to which humans may be exposed in each relevant
manufacturing or processing scenario.
3. Health effects data including pharmacokinetics, genotoxicity,
subchronic toxicity, reproductive and developmental toxicity, and
any human data from occupationally exposed workers.
The ITC seeks this information in order to adequately assess the
extent and degree of exposure and potential hazard associated with
the various forms of vanadium.
In addition, the ITC is concerned that some of these compounds
may be released into fly ash ponds at power plants, petroleum and
chemical refineries, and mining sites and could be toxic to avian
and wildlife species as exemplified by a recent report of dead and
dying Canada geese at a petroleum refinery fly ash pond in Delaware.
In these geese, the vanadium concentrations in pooled liver and
kidney samples were 57 and 226 [mu]g/gram (g) dry weight,
respectively. Background concentrations of vanadium in various
tissues of higher vertebrates, including waterfowl, rarely exceed 1
[mu]g/g dry weight. Limited data are available on vanadium toxicity
in birds and other wildlife making it difficult to interpret the
findings from the geese die-off.
The ITC knows that vanadium is released into impoundments at 172
facilities in 33 states and that the TRI does not have vanadium
concentrations for these impoundments. The ITC is soliciting data on
concentrations and species of vanadium compounds in impoundments at
power plants, petroleum and chemical refineries, and mining sites
and information on the use, release, and presence of vanadium
compounds at these facilities. The ITC needs these data and
information to determine if avian wildlife in the vicinity of the
172 facilities are at risk from exposure to vanadium compounds. If
you have any questions regarding the applicability of this action to
a particular entity, consult the technical person listed under FOR
FURTHER INFORMATION CONTACT.
IV. Revisions to the TSCA Section 4(e) Priority Testing List
A. Chemicals Added to the Priority Testing List: HPV Orphan
Chemicals
1. Recommendation. EPA requests that the ITC add the category
HPV orphan chemicals listed in Appendix A of this report to the
Priority Testing List to obtain importation, production, use, and
exposure information as well as unpublished physical/chemical
property, environmental fate, health effects, and ecological effects
information to meet U.S. Government data needs.
2. Rationale for recommendation. While the success of the HPV
Challenge Program has been significant, hundreds of chemicals that
were eligible for sponsorship in the Program continue to remain
unsponsored. These chemicals are referred to as ``orphans.'' There
is little or no publicly available information regarding the
potential hazards associated with these chemicals. EPA remains
committed to obtain basic screening level hazard information on
these chemicals through voluntary sponsorship, as well as through
TSCA information gathering and test rules, as necessary.
3. Supporting information. In developing the list of HPV orphan
chemicals presented in Appendix A of this report, EPA considered all
of the HPV orphan chemicals and then removed selected HPV orphan
chemicals. The HPV orphan chemicals presented in Appendix A of this
report do not include those HPV orphan chemicals that:
a. Had 2002 Inventory Update rule reported production/
importation volumes > one million pounds (http://www.epa.gov/oppt/
iur/iur02/index.htm/ ) and were proposed for testing in the first
HPV test rule (Ref. 8).
b. Meet the ``No Longer HPV'' criteria (i.e., chemicals with
production/importation volumes < 1 million pounds based on 1998 and
2002 Inventory Update Rule data (http://www.epa.gov/oppt/iur/iur02/
index.htm/)).
c. Are being considered for a second HPV TSCA section 4 test
rule because they may meet the TSCA section 4(a)(1)(B) statutory
requirements.
At EPA's request, the ITC encourages manufacturers of these
chemicals to visit the EPA's HPV Challenge Program web site (http://
www.epa.gov/opptintr/chemrtk/volchall.htm/) and to make a commitment
to sponsor these chemicals at the present time, before regulatory
actions are initiated. EPA will initiate development of TSCA section
8(a) PAIR and 8(d) HaSDR rules soon after these chemicals are added
to the Priority Testing List and the ITC's 55\th\ Report is
published in the Federal Register. Also at EPA's request, the ITC
encourages the submission of robust summaries of studies submitted
under the TSCA section 8(d) HaSDR rule to facilitate EPA's review of
the unpublished TSCA section 8(d) studies (see USEPA. 1999. Draft
Guidance on Developing Robust Summaries. October 22, 1999 (http://
www.epa.gov/chemrtk/robsumgd.htm/)). While some of the HPV orphan
chemicals have been previously added to the TSCA section 8(d) HaSDR
rule, all of the sunset dates for these chemicals have expired (see
Appendix A of this report), thus new and so far unreported studies
would need to be submitted. Information about the environmental fate
and potential hazards associated with these chemicals when combined
with information about exposure and uses will allow the EPA and
others to evaluate and prioritize potential health and environmental
effects and determine the need for test rules under TSCA section
4(a). If you have any questions regarding the applicability of this
action to a particular entity, consult the technical person listed
under FOR FURTHER INFORMATION CONTACT.
4. Information needs. For each individual substance listed in
Appendix A of this report, EPA needs the following information to
assess the extent and degree of exposure and potential hazard
associated with these substances:
a. Production, importation, processing, use and associated
exposure information that is captured under the TSCA section 8(a)
PAIR form.
b. Unpublished studies of:
i. Physical/chemical properties and environmental fate for the
properties listed in 40 CFR 716.50 as well as melting point and
boiling point.
ii. Health effects including pharmacokinetics, genotoxicity,
acute toxicity, subacute toxicity, subchronic toxicity, chronic
toxicity, reproductive toxicity, developmental toxicity,
immunotoxicity, neurotoxicity, and oncogenicity/carcinogenicity.
iii. Ecological effects including acute and chronic toxicity
studies of aquatic and terrestrial vertebrates and invertebrates and
aquatic plants.
c. Only studies where the recommended HPV orphan chemical is >=
90% of the test substance by weight should be submitted. In
[[Page 7368]]
addition, only studies that were conducted using TSCA, Federal
Insecticide, Fungicide, and Rodenticide Act (FIFRA), Organization
for Economic Cooperation and Development (OECD), or other
internationally accepted test guidelines or voluntary consensus
standards should be submitted. Studies performed where the
recommended HPV orphan chemical is < 90% of the test substance by
weight are not requested at this time.
B. Chemicals Removed From the Priority Testing List
1. 3-Amino-5-mercapto-1,2,4-triazole. 3-Amino-5-mercapto-1,2,4-
triazole (Chemical Abstracts Service Registry Number (CAS No.)
16691-43-3 ) was added to the Priority Testing List in the ITC's
42\nd\ Report to obtain annual production/importation volumes and
trends, use, exposure, and health effects data (Ref. 9). The
addition was based on concerns that 3-amino-5-mercapto-1,2,4-
triazole was structurally related to 3-amino-1,2,4-triazole
(Amitrol[reg]), a herbicide that affects thyroid hormone activity
(Ref. 10). In response to the ITC's request, the EPA added 3-amino-
5-mercapto-1,2,4-triazole to the July 24, 2000, PAIR rule (Ref. 11)
and the May 4, 2004 HaSDR rule (Ref. 5). Numerous studies were
submitted in response to the HaSDR rule. These studies are
summarized in this unit. 3-Amino-5-mercapto-1,2,4-triazole was
positive in the mouse bone marrow micronucleus test, clastogenic to
rat lymphocytes, but not mutagenic in the Ames assay using strains
TA98, 100, 1535, and 1537 or in the E. coli assay, using strain WP2
uvrA-. 3-Amino-5-mercapto-1,2,4-triazole was a mild eye and skin
irritant, but not a skin sensitizer. In a 4-week inhalation study
the no observed effect level of 3-amino-5-mercapto-1,2,4-triazole
was 20 milligram/meter cubed (mg/m\3\).
3-Amino-5-mercapto-1,2,4-triazole is being removed from the
Priority Testing List because information submitted in response to
the PAIR rule suggested that 3-amino-5-mercapto-1,2,4-triazole is an
on-site intermediate and the production/importation volumes were
lower than the 250,000 pounds of 3-amino-5-mercapto-1,2,4-triazole
imported into the United States in 1993 (Ref. 9).
2. Glycoluril. Glycoluril (CAS No. 496-46-8) was also added to
the Priority Testing List in the ITC's 42\nd\ Report to obtain
annual production/importation volumes and trends, use, exposure, and
health effects data. The addition was based on a potential for human
exposure and a suspicion of carcinogenicity (Ref. 9). In response to
the ITC's request, the EPA added glycoluril to the July 24, 2000
PAIR rule (Ref. 11) and the May 4, 2004 HaSDR rule (Ref. 5). No
studies were submitted in response to the HaSDR rule.
Glycoluril is being removed from the Priority Testing List
because information submitted in response to the PAIR rule suggested
that glycoluril is an on-site intermediate and the production/
importation volumes were less than the 10,000 to 1,000,000 pounds of
non-CBI annual production/importation volumes reported to the EPA in
1986, 1990, and 1994 (Ref. 9).
3. Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-4-
(trifluoromethyl)-. Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-
4-(trifluoromethyl)- (aka 3-Chlorotrifluralin (CAS No. 29091-20-1)
was added to the Priority Testing List in the ITC's 48\th\ Report to
obtain information on uses, exposures, environmental releases,
pharmacokinetics, subchronic toxicity, mutagenicity, reproductive
and developmental effects, carcinogenicity, and ecological effects
(Ref. 12). Benzenamine, 3-chloro-2,6-dinitro-N,N-dipropyl-4-
(trifluoromethyl)- was added to the Priority Testing List because it
has an estimated bioconcentration factor (BCF) of 7,700 and is a
chlorinated analog of trifluralin (CAS No. 1582-09-8), the herbicide
that causes adverse effects in experimental animals and is
considered to be a possible human carcinogen by the EPA (Ref. 12).
In response to the ITC's request, the EPA added benzenamine, 3-
chloro-2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- to the June 11,
2003 PAIR rule (Ref. 4) and the May 4, 2004 TSCA section 8(d) HaSDR
rule (Ref. 5). No information was submitted in response to the PAIR
or HaSDR rules. The ITC is removing benzenamine, 3-chloro-2,6-
dinitro-N,N-dipropyl-4-(trifluoromethyl)- from the Priority Testing
List because the PAIR rule did not provide any additional exposure
information implying that benzenamine, 3-chloro-2,6-dinitro-N,N-
dipropyl-4-(trifluoromethyl)- is not produced at greater than 1,000
pounds per site.
4. Stannane, dimethylbis[(1-oxoneodecyl)oxy]-. Stannane,
dimethylbis[(1-oxoneodecyl)oxy]- (CAS No. 68928-76-7) was added to
the Priority Testing List in the ITC's 49\th\ Report to obtain use,
exposure, environmental fate, health effects, and ecological effects
data (Ref. 13). Stannane, dimethylbis[(1-oxoneodecyl)oxy]- was added
to the Priority Testing List because it has an estimated BCF of
8,600 and signs of toxicity, including neurotoxic effects that were
observed in a rat oral gavage study (Ref. 13).
In response to the ITC's request, the EPA added stannane,
dimethylbis[(1-oxoneodecyl)oxy]- to the June 11, 2003 PAIR rule
(Ref. 4) and the May 4, 2004 TSCA section 8(d) HaSDR rule (Ref. 5).
No information was submitted in response to the HaSDR rule. The ITC
is removing stannane, dimethylbis[(1-oxoneodecyl)oxy]- from the
Priority Testing List because the information submitted in response
to the PAIR rule suggested that the production/importation volumes
of stannane, dimethylbis[(1-oxoneodecyl)oxy]- were not greater than
the 10,000-500,000 pounds of non-CBI production/importation volumes
reported to the EPA in 2002 (http://www.epa.gov/oppt/iur/iur02/
index.htm/).
5. Benzene, 1,3,5-tribromo-2-(2-propenyloxy)-. Benzene, 1,3,5-
tribromo-2-(2-propenyloxy)- (CAS No. 3278-89-5) was added to the
Priority Testing List in the ITC's 50\th\ Report to obtain use,
exposure, environmental fate, health effects, and ecological effects
data (Ref. 14). Benzene, 1,3,5-tribromo-2-(2-propenyloxy)- was added
to the Priority Testing List because of an estimated BCF of 4,000
and potential for exposure from its use as a flame retardant for
expanded polystyrene insulation board (Ref. 14).
In response to the ITC's request, the EPA added benzene, 1,3,5-
tribromo-2-(2-propenyloxy)- to the June 11, 2003 PAIR rule (Ref. 4)
and the May 4, 2004 TSCA section 8(d) HaSDR rule (Ref. 5).
Information submitted in response to the HaSDR rule indicated that
the concentrated chemical may be slightly irritating to the skin.
The ITC is removing benzene, 1,3,5-tribromo-2-(2-propenyloxy)- from
the Priority Testing List because the information submitted in
response to the PAIR rule suggested that the production/importation
volumes of benzene, 1,3,5-tribromo-2-(2-propenyloxy)- were not
greater than 10,000-500,000 pounds of non-CBI production/importation
volumes reported to the EPA in 2002 (http://www.epa.gov/oppt/iur/
iur02/index.htm/).
6. 1-Triazene, 1,3-diphenyl-. 1-Triazene, 1,3-diphenyl- (aka
diazoaminobenzene (CAS No. 136-35-6) was added to the Priority
Testing List in the ITC's 50\th\ Report to obtain annual production/
importation volumes and trends, use, exposure, and health effects
data (Ref. 14). 1-Triazene, 1,3-diphenyl- was added to the Priority
Testing List because it is a predicted carcinogen based on its
metabolism and similarity in toxic effects to benzene and aniline
(Ref. 14).
In response to the ITC's request, the EPA added 1-triazene, 1,3-
diphenyl- to the June 11, 2003 PAIR rule (Ref. 4) and the May 4,
2004 TSCA section 8(d) HaSDR rule (Ref. 5). No information was
submitted in response to the PAIR or HaSDR rules. The ITC is
removing 1-triazene, 1,3-diphenyl- from the Priority Testing List
because the PAIR rule did not provide any additional exposure
information implying that 1-triazene, 1,3-diphenyl- is not produced
at greater than 1,000 pounds per site.
V. References
1. EPA. 1998. Revisions to Reporting Regulations Under TSCA
Section 8(d). Direct Final Rule. Federal Register (63 FR 15765,
April 1, 1998) (FRL-5750-4). Available online at: http://
www.epa.gov/fedrgstr/.
2. ITC. 2004. Fifty-Third Report of the ITC. Federal Register
(69 FR 2467, January 15, 2004) (FRL-7335-2). Available online at:
http://www.epa.gov/fedrgstr/.
3. EPA. 2004. Preliminary Assessment Information Reporting;
Addition of Certain Chemicals. Final Rule. Federal Register (69 FR
70552, December 7, 2004) (FRL-7366-8). Available online at: http://
www.epa.gov/fedrgstr/.
4. EPA. 2003. Preliminary Assessment Information Reporting;
Addition of Certain Chemicals. Final Rule. Federal Register (68 FR
34832, June 11, 2003) (FRL-7306-7). Available online at: http://
www.epa.gov/fedrgstr/.
5. EPA. 2004. Health and Safety Data Reporting; Addition of
Certain Chemicals. Final Rule. Federal Register (69 FR 24517, May 4,
2004) (FRL-7322-8). Available online at: http://www.epa.gov/
fedrgstr/.
6. ITC. 2003. Fifty-First Report of the ITC. Federal Register
(68 FR 8976, February 26, 2003) (FRL-7285-7). Available online at:
http://www.epa.gov/fedrgstr/.
7. ITC. 2004. Fifty-Fourth Report of the ITC. Federal Register
(69 FR 33527, June 15, 2004) (FRL-7359-6). Available online at:
http://www.epa.gov/fedrgstr/.
8. EPA. 2000. Testing of Certain High Production Volume
Chemicals. Proposed
[[Page 7369]]
Rule. Federal Register (65 FR 81658, December 26, 2000) (FRL-6758-
4). Available online at: http://www.epa.gov/fedrgstr/.
9. ITC. 1998. Forty-Second Report of the ITC. Federal Register
(63 FR 42554, August 7, 1998) (FRL-5797-8). Available online at:
http://www.epa.gov/fedrgstr/.
10. Takaoka, M., M. Teranishi, and S. Manabe. 1994. Structure-
Activity Relationships in 5-Substituted 3-Amino-1,2,4-Triazoles-
Induced Goiters in Rats. Journal of Toxicology and Pathology. 7:429-
434.
11. EPA. 2000. Preliminary Assessment Information Reporting;
Addition of Certain Chemicals. Final Rule. Federal Register (65 FR
45535, July 24, 2000) (FRL-6597-3). Available online at: http://
www.epa.gov/fedrgstr/.
12. ITC. 2001. Forty-Eighth Report of the ITC. Federal Register
(66 FR 51276, October 5, 2001) (FRL-6786-7). Available online at:
http://www.epa.gov/fedrgstr/.
13. ITC. 2002. Forty-Ninth Report of the ITC. Federal Register
(67 FR 10298, March 6, 2002) (FRL-6820-8). Available online at:
http://www.epa.gov/fedrgstr/.
14. ITC. 2002. Fiftieth Report of the ITC. Federal Register (67
FR 49530, July 30, 2002) (FRL-7183-7). Available online at: http://
www.epa.gov/fedrgstr/.
VI. The TSCA Interagency Testing Committee
Statutory Organizations and Their Representatives
Council on Environmental Quality
Vacant
Department of Commerce
National Institute of Standards and Technology
Dianne Poster, Member
Peter Barker, Alternate
National Oceanographic and AtmosphericAdministration
Thomas P. O'Connor, Member, Chair
Teri Rowles, Alternate
Environmental Protection Agency
Gerry Brown, Member
Paul Campanella, Alternate
National Cancer Institute
Alan Poland, Member
Shen Yang, Alternate
National Institute of Environmental Health Sciences
Barbara Shane, Member
Scott Masten, Alternate
National Institute for Occupational Safety and Health
Mark Toraason, Member
Dennis W. Lynch, Alternate
National Science Foundation
Marge Cavanaugh, Member
Parag R. Chitnis, Alternate
Occupational Safety and Health Administration
Maureen Ruskin, Member
Liaison Organizations and Their Representatives
Agency for Toxic Substances and Disease Registry
Daphne Moffett, Member
Consumer Product Safety Commission
Treye Thomas, Member
Jacqueline Ferrante, Alternate
Department of Agriculture
Clifford P. Rice, Member, Vice Chair
Laura L. McConnell, Alternate
Department of Defense
Warren Jederberg, Member
Department of the Interior
Barnett A. Rattner, Member
Food and Drug Administration
Kirk Arvidson, Alternate
Ronald F. Chanderbhan, Alternate
National Library of Medicine
Vera W. Hudson, Member
National Toxicology Program
NIEHS, FDA, and NIOSH Members
Technical Support Contractor
Syracuse Research Corporation
ITC Staff
John D. Walker, Director
Norma S. L. Williams, Executive Assistant
TSCA Interagency Testing Committee (7401), Office of Pollution
Prevention and Toxics, Environmental Protection Agency, 1200
Pennsylvania Ave., NW., Washington, DC 20460-0001; e-mail address:
[email protected]; url: http://www.epa.gov/ opptintr/itc/.
Appendix A--Chemical Abstracts Service Registry Number (CAS No.), TSCA Inventory Names and Previous TSCA Section
8(d) Rule Sunset Dates of HPV Orphan Chemicals for Which the ITC is Requesting that the EPA Add to TSCA Section
8(a) and 8(d) Rules
----------------------------------------------------------------------------------------------------------------
Previous TSCA section 8(d) rule
CAS No. TSCA Inventory Name sunset date
----------------------------------------------------------------------------------------------------------------
62-56-6 Thiourea ..................................
------------------------------------------------------------------------------
74-97-5 Methane, bromochloro- 6/1/1997
------------------------------------------------------------------------------
75-34-3 Ethane, 1,1-dichloro- 6/1/1997
------------------------------------------------------------------------------
75-46-7 Methane, trifluoro- ..................................
------------------------------------------------------------------------------
77-76-9 Propane, 2,2-dimethoxy- ..................................
------------------------------------------------------------------------------
81-07-2 1,2-Benzisothiazol-3(2H)-one, 1,1- ..................................
dioxide
------------------------------------------------------------------------------
81-16-3 1-Naphthalenesulfonic acid, 2-amino- ..................................
------------------------------------------------------------------------------
81-84-5 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione 6/30/1998
------------------------------------------------------------------------------
83-41-0 Benzene, 1,2-dimethyl-3-nitro- ..................................
------------------------------------------------------------------------------
84-69-5 1,2-Benzenedicarboxylic acid, bis(2- 10/4/1992
methylpropyl) ester
------------------------------------------------------------------------------
85-40-5 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a- ..................................
tetrahydro-
------------------------------------------------------------------------------
90-43-7 [1,1'-Biphenyl]-2-ol ..................................
------------------------------------------------------------------------------
91-68-9 Phenol, 3-(diethylamino)- ..................................
------------------------------------------------------------------------------
94-75-7 Acetic acid, (2,4-dichlorophenoxy)- ..................................
------------------------------------------------------------------------------
[[Page 7370]]
94-96-2 1,3-Hexanediol, 2-ethyl- ..................................
------------------------------------------------------------------------------
95-94-3 Benzene, 1,2,4,5-tetrachloro- 10/4/1992
------------------------------------------------------------------------------
96-22-0 3-Pentanone ..................................
------------------------------------------------------------------------------
96-23-1 2-Propanol, 1,3-dichloro- ..................................
------------------------------------------------------------------------------
97-00-7 Benzene, 1-chloro-2,4-dinitro- ..................................
------------------------------------------------------------------------------
98-09-9 Benzenesulfonyl chloride ..................................
------------------------------------------------------------------------------
98-16-8 Benzenamine, 3-(trifluoromethyl)- ..................................
------------------------------------------------------------------------------
98-56-6 Benzene, 1-chloro-4-(trifluoromethyl)- 4/29/1993
------------------------------------------------------------------------------
99-51-4 Benzene, 1,2-dimethyl-4-nitro- ..................................
------------------------------------------------------------------------------
100-64-1 Cyclohexanone, oxime ..................................
------------------------------------------------------------------------------
101-34-8 9-Octadecenoic acid, 12-(acetyloxy)-, ..................................
1,2,3-propanetriyl ester,
(9Z,9'Z,9''Z,12R,12'R,12''R)-
------------------------------------------------------------------------------
104-66-5 Benzene, 1,1'-[1,2- ..................................
ethanediylbis(oxy)]bis-
------------------------------------------------------------------------------
104-93-8 Benzene, 1-methoxy-4-methyl- ..................................
------------------------------------------------------------------------------
107-39-1 1-Pentene, 2,4,4-trimethyl- ..................................
------------------------------------------------------------------------------
107-40-4 2-Pentene, 2,4,4-trimethyl- ..................................
------------------------------------------------------------------------------
107-45-9 2-Pentanamine, 2,4,4-trimethyl- ..................................
------------------------------------------------------------------------------
110-18-9 1,2-Ethanediamine, N,N,N',N'-tetramethyl- ..................................
------------------------------------------------------------------------------
110-33-8 Hexanedioic acid, dihexyl ester ..................................
------------------------------------------------------------------------------
111-44-4 Ethane, 1,1'-oxybis[2-chloro- ..................................
------------------------------------------------------------------------------
111-85-3 Octane, 1-chloro- ..................................
------------------------------------------------------------------------------
111-91-1 Ethane, 1,1'-[methylenebis(oxy)]bis[2- ..................................
chloro-
------------------------------------------------------------------------------
118-90-1 Benzoic acid, 2-methyl- ..................................
------------------------------------------------------------------------------
119-33-5 Phenol, 4-methyl-2-nitro- 6/30/1998
------------------------------------------------------------------------------
121-69-7 Benzenamine, N,N-dimethyl- 6/30/1998
------------------------------------------------------------------------------
121-82-4 1,3,5-Triazine, hexahydro-1,3,5-trinitro- ..................................
------------------------------------------------------------------------------
124-63-0 Methanesulfonyl chloride ..................................
------------------------------------------------------------------------------
127-68-4 Benzenesulfonic acid, 3-nitro-, sodium ..................................
salt
------------------------------------------------------------------------------
131-57-7 Methanone, (2-hydroxy-4- ..................................
methoxyphenyl)phenyl-
------------------------------------------------------------------------------
137-20-2 Ethanesulfonic acid, 2-[methyl[(9Z)-1- 12/28/1994
oxo-9- octadecenyl]amino]-, sodium salt
------------------------------------------------------------------------------
138-25-0 1,3-Benzenedicarboxylic acid, 5-sulfo-, ..................................
1,3-dimethyl ester
------------------------------------------------------------------------------
139-40-2 1,3,5-Triazine-2,4-diamine, 6-chloro- ..................................
N,N'-bis(1-methylethyl)-
------------------------------------------------------------------------------
140-08-9 Ethanol, 2-chloro-, phosphite (3:1) ..................................
------------------------------------------------------------------------------
140-93-2 Carbonodithioic acid, O-(1-methylethyl) ..................................
ester, sodium salt
------------------------------------------------------------------------------
142-73-4 Glycine, N-(carboxymethyl)- ..................................
------------------------------------------------------------------------------
[[Page 7371]]
150-50-5 Phosphorotrithious acid, tributyl ester ..................................
------------------------------------------------------------------------------
307-35-7 1-Octanesulfonyl fluoride, ..................................
1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-
heptadecafluoro-
------------------------------------------------------------------------------
330-54-1 Urea, N'-(3,4-dichlorophenyl)-N,N- ..................................
dimethyl-
------------------------------------------------------------------------------
460-00-4 Benzene, 1-bromo-4-fluoro- ..................................
------------------------------------------------------------------------------
506-51-4 1-Tetracosanol ..................................
------------------------------------------------------------------------------
506-52-5 1-Hexacosanol ..................................
------------------------------------------------------------------------------
513-74-6 Carbamodithioic acid, monoammonium salt ..................................
------------------------------------------------------------------------------
515-40-2 Benzene, (2-chloro-1,1-dimethylethyl)- ..................................
------------------------------------------------------------------------------
529-33-9 1-Naphthalenol, 1,2,3,4-tetrahydro- ..................................
------------------------------------------------------------------------------
529-34-0 1(2H)-Naphthalenone, 3,4-dihydro- ..................................
------------------------------------------------------------------------------
542-75-6 1-Propene, 1,3-dichloro- ..................................
------------------------------------------------------------------------------
542-92-7 1,3-Cyclopentadiene 6/30/1998
------------------------------------------------------------------------------
557-61-9 1-Octacosanol ..................................
------------------------------------------------------------------------------
563-72-4 Ethanedioic acid, calcium salt (1:1) ..................................
------------------------------------------------------------------------------
579-66-8 Benzenamine, 2,6-diethyl- ..................................
------------------------------------------------------------------------------
590-19-2 1,2-Butadiene ..................................
------------------------------------------------------------------------------
592-45-0 1,4-Hexadiene ..................................
------------------------------------------------------------------------------
597-31-9 Propanal, 3-hydroxy-2,2-dimethyl- 6/30/1998
------------------------------------------------------------------------------
598-72-1 Propanoic acid, 2-bromo- ..................................
------------------------------------------------------------------------------
617-94-7 Benzenemethanol, .alpha.,.alpha.- ..................................
dimethyl-
------------------------------------------------------------------------------
625-55-8 Formic acid, 1-methylethyl ester ..................................
------------------------------------------------------------------------------
628-13-7 Pyridine, hydrochloride ..................................
------------------------------------------------------------------------------
628-96-6 1,2-Ethanediol, dinitrate ..................................
------------------------------------------------------------------------------
645-62-5 2-Hexenal, 2-ethyl- ..................................
------------------------------------------------------------------------------
693-07-2 Ethane, 1-chloro-2-(ethylthio)- ..................................
------------------------------------------------------------------------------
693-95-8 Thiazole, 4-methyl- ..................................
------------------------------------------------------------------------------
756-80-9 Phosphorodithioic acid, O,O-dimethyl ..................................
ester
------------------------------------------------------------------------------
870-72-4 Methanesulfonic acid, hydroxy-, ..................................
monosodium salt
------------------------------------------------------------------------------
928-72-3 Glycine, N-(carboxymethyl)-, disodium ..................................
salt
------------------------------------------------------------------------------
939-97-9 Benzaldehyde, 4-(1,1-dimethylethyl)- 11/9/1993
------------------------------------------------------------------------------
1000-82-4 Urea, (hydroxymethyl)- 7/1/1993
------------------------------------------------------------------------------
1002-69-3 Decane, 1-chloro- ..................................
------------------------------------------------------------------------------
1111-78-0 Carbamic acid, monoammonium salt ..................................
------------------------------------------------------------------------------
1115-20-4 Propanoic acid, 3-hydroxy-2,2-dimethyl-, ..................................
3-hydroxy-2,2-dimethylpropyl ester
------------------------------------------------------------------------------
1401-55-4 Tannins ..................................
------------------------------------------------------------------------------
[[Page 7372]]
1445-45-0 Ethane, 1,1,1-trimethoxy- ..................................
------------------------------------------------------------------------------
1459-93-4 1,3-Benzenedicarboxylic acid, dimethyl ..................................
ester
------------------------------------------------------------------------------
1498-51-7 Phosphorodichloridic acid, ethyl ester 11/9/1993
------------------------------------------------------------------------------
1558-33-4 Silane, dichloro(chloromethyl)methyl- ..................................
------------------------------------------------------------------------------
1646-75-9 Propanal, 2-methyl-2-(methylthio)-, ..................................
oxime
------------------------------------------------------------------------------
1691-99-2 1-Octanesulfonamide, N-ethyl- ..................................
1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-
heptadecafluoro-N-(2-hydroxyethyl)-
------------------------------------------------------------------------------
1738-25-6 Propanenitrile, 3-(dimethylamino)- ..................................
------------------------------------------------------------------------------
1912-24-9 1,3,5-Triazine-2,4-diamine, 6-chloro-N- ..................................
ethyl-N'-(1-methylethyl)-
------------------------------------------------------------------------------
1918-02-1 2-Pyridinecarboxylic acid, 4-amino-3,5,6- ..................................
trichloro-
------------------------------------------------------------------------------
1929-82-4 Pyridine, 2-chloro-6-(trichloromethyl)- ..................................
------------------------------------------------------------------------------
2152-64-9 Benzenamine, N-phenyl-4-[[4- ..................................
(phenylamino)phenyl][4-(phenylimino)-
2,5-cyclohexadien-1-ylidene]methyl]-,
monohydrochloride
------------------------------------------------------------------------------
2210-79-9 Oxirane, [(2-methylphenoxy)methyl]- 10/4/1992
------------------------------------------------------------------------------
2372-45-4 1-Butanol, sodium salt ..................................
------------------------------------------------------------------------------
2409-55-4 Phenol, 2-(1,1-dimethylethyl)-4-methyl- ..................................
------------------------------------------------------------------------------
2425-54-9 Tetradecane, 1-chloro- ..................................
------------------------------------------------------------------------------
2494-89-5 Ethanol, 2-[(4-aminophenyl)sulfonyl]-, ..................................
hydrogen sulfate (ester)
------------------------------------------------------------------------------
2524-03-0 Phosphorochloridothioic acid, O,O- ..................................
dimethyl ester
------------------------------------------------------------------------------
2611-00-9 3-Cyclohexene-1-carboxylic acid, 3- ..................................
cyclohexen-1-ylmethyl ester
------------------------------------------------------------------------------
2691-41-0 1,3,5,7-Tetrazocine, octahydro-1,3,5,7- ..................................
tetranitro-
------------------------------------------------------------------------------
2702-72-9 Acetic acid, (2,4-dichlorophenoxy)-, ..................................
sodium salt
------------------------------------------------------------------------------
2814-20-2 4(1H)-Pyrimidinone, 6-methyl-2-(1- ..................................
methylethyl)-
------------------------------------------------------------------------------
2905-62-6 Benzoyl chloride, 3,5-dichloro- ..................................
------------------------------------------------------------------------------
2915-53-9 2-Butenedioic acid (2Z)-, dioctyl ester ..................................
------------------------------------------------------------------------------
3039-83-6 Ethenesulfonic acid, sodium salt ..................................
------------------------------------------------------------------------------
3088-31-1 Ethanol, 2-[2-(dodecyloxy)ethoxy]-, ..................................
hydrogen sulfate, sodium salt
------------------------------------------------------------------------------
3132-99-8 Benzaldehyde, 3-bromo- 6/30/1998
------------------------------------------------------------------------------
3338-24-7 Phosphorodithioic acid, O,O-diethyl ..................................
ester, sodium salt
------------------------------------------------------------------------------
3386-33-2 Octadecane, 1-chloro- ..................................
------------------------------------------------------------------------------
3586-14-9 Benzene, 1-methyl-3-phenoxy- 6/30/1998
------------------------------------------------------------------------------
3710-84-7 Ethanamine, N-ethyl-N-hydroxy- ..................................
------------------------------------------------------------------------------
3779-63-3 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, ..................................
1,3,5-tris(6-isocyanatohexyl)-
------------------------------------------------------------------------------
3965-55-7 1,3-Benzenedicarboxylic acid, 5-sulfo-, ..................................
1,3-dimethyl ester, sodium salt
------------------------------------------------------------------------------
4035-89-6 Imidodicarbonic diamide, N,N',2-tris(6- 11/9/1993
isocyanatohexyl)-
------------------------------------------------------------------------------
4080-31-3 3,5,7-Triaza-1- ..................................
azoniatricyclo[3.3.1.13,7]decane, 1-(3-
chloro-2-propenyl)-, chloride
------------------------------------------------------------------------------
[[Page 7373]]
4170-30-3 2-Butenal ..................................
------------------------------------------------------------------------------
4300-97-4 Propanoyl chloride, 3-chloro-2,2- ..................................
dimethyl-
------------------------------------------------------------------------------
4316-73-8 Glycine, N-methyl-, monosodium salt ..................................
------------------------------------------------------------------------------
4860-03-1 Hexadecane, 1-chloro- ..................................
------------------------------------------------------------------------------
5026-74-4 Oxiranemethanamine, N-[4- ..................................
(oxiranylmethoxy)phenyl]-N-
(oxiranylmethyl)-
------------------------------------------------------------------------------
5216-25-1 Benzene, 1-chloro-4-(trichloromethyl)- ..................................
------------------------------------------------------------------------------
5460-09-3 2,7-Naphthalenedisulfonic acid, 4-amino- ..................................
5-hydroxy-, monosodium salt
------------------------------------------------------------------------------
5915-41-3 1,3,5-Triazine-2,4-diamine, 6-chloro-N- ..................................
(1,1-dimethylethyl)-N'-ethyl-
------------------------------------------------------------------------------
6473-13-8 2-Naphthalenesulfonic acid, 6-[(2,4- ..................................
diaminophenyl)azo]-3-[[4-[[4-[[7-[(2,4-
diaminophenyl)azo]-1-hydroxy-3-sulfo-2-
naphthalenyl]azo]phenyl]amino]-3-
sulfophenyl]azo]-4-hydroxy-, trisodium
salt
------------------------------------------------------------------------------
6863-58-7 Butane, 2,2'-oxybis- ..................................
------------------------------------------------------------------------------
6865-35-6 Octadecanoic acid, barium salt ..................................
------------------------------------------------------------------------------
7320-37-8 Oxirane, tetradecyl- 10/40/1992
------------------------------------------------------------------------------
7446-81-3 2-Propenoic acid, sodium salt ..................................
------------------------------------------------------------------------------
7795-95-1 1-Octanesulfonyl chloride ..................................
------------------------------------------------------------------------------
8001-58-9 Creosote ..................................
------------------------------------------------------------------------------
10265-69-7 Glycine, N-phenyl-, monosodium salt ..................................
------------------------------------------------------------------------------
13749-94-5 Ethanimidothioic acid, N-hydroxy-, 6/30/1998
methyl ester
------------------------------------------------------------------------------
13826-35-2 Benzenemethanol, 3-phenoxy- ..................................
------------------------------------------------------------------------------
14143-60-3 2-Pyridinecarbonitrile, 4-amino-3,5,6- ..................................
trichloro-
------------------------------------------------------------------------------
14666-94-5 9-Octadecenoic acid (9Z)-, cobalt salt ..................................
------------------------------------------------------------------------------
17103-31-0 Urea, sulfate (2:1) ..................................
------------------------------------------------------------------------------
17321-47-0 Phosphoramidothioic acid, O,O-dimethyl ..................................
ester
------------------------------------------------------------------------------
17976-43-1 2,4,6,8,3,5,7- ..................................
Benzotetraoxatriplumbacycloundecin-
3,5,7-triylidene, 1,9-dihydro-1,9-dioxo-
------------------------------------------------------------------------------
19438-61-0 1,3-Isobenzofurandione, 5-methyl- ..................................
------------------------------------------------------------------------------
19525-59-8 Glycine, N-phenyl-, monopotassium salt ..................................
------------------------------------------------------------------------------
20068-02-4 2-Butenenitrile, 2-methyl-, (2Z)- ..................................
------------------------------------------------------------------------------
20227-53-6 Phosphorous acid, 2-(1,1-dimethylethyl)- ..................................
4-[1-[3-(1,1-dimethylethyl)-4-
hydroxyphenyl]-1-methylethyl]phenyl
bis(4-nonylphenyl) ester
------------------------------------------------------------------------------
20469-71-0 Hydrazinecarbodithioic acid, compd. with ..................................
hydrazine (1:1)
------------------------------------------------------------------------------
21351-39-3 Urea, sulfate (1:1) ..................................
------------------------------------------------------------------------------
22527-63-5 Propanoic acid, 2-methyl-, 3- ..................................
(benzoyloxy)-2,2,4-trimethylpentyl
ester
------------------------------------------------------------------------------
24448-09-7 1-Octanesulfonamide, ..................................
1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-
heptadecafluoro-N-(2-hydroxyethyl)-N-
methyl-
------------------------------------------------------------------------------
24615-84-7 2-Propenoic acid, 2-carboxyethyl ester ..................................
------------------------------------------------------------------------------
[[Page 7374]]
24794-58-9 Formic acid, compd. with 2,2',2''- ..................................
nitrilotris[ethanol] (1:1)
------------------------------------------------------------------------------
25154-38-5 Piperazineethanol ..................................
------------------------------------------------------------------------------
25168-05-2 Benzene, chloromethyl- ..................................
------------------------------------------------------------------------------
25168-06-3 Phenol, (1-methylethyl)- 11/9/1993
------------------------------------------------------------------------------
25321-41-9 Benzenesulfonic acid, dimethyl- ..................................
------------------------------------------------------------------------------
25383-99-7 Octadecanoic acid, 2-(1-carboxyethoxy)-1- ..................................
methyl-2-oxoethyl ester, sodium salt
------------------------------------------------------------------------------
25586-42-9 Phosphorous acid, tris(methylphenyl) ..................................
ester
------------------------------------------------------------------------------
25646-71-3 Methanesulfonamide, N-[2-[(4-amino-3- ..................................
methylphenyl)ethylamino]ethyl]-,
sulfate (2:3)
------------------------------------------------------------------------------
26377-29-7 Phosphorodithioic acid, O,O-dimethyl ..................................
ester, sodium salt
------------------------------------------------------------------------------
26401-27-4 Phosphorous acid, isooctyl diphenyl ..................................
ester
------------------------------------------------------------------------------
26680-54-6 2,5-Furandione, dihydro-3-(octenyl)- ..................................
------------------------------------------------------------------------------
27193-28-8 Phenol, (1,1,3,3-tetramethylbutyl)- 6/30/1998
------------------------------------------------------------------------------
28106-30-1 Benzene, ethenylethyl- ..................................
------------------------------------------------------------------------------
28188-24-1 Octadecanoic acid, 2-(hydroxymethyl)-2- ..................................
[[(1-oxooctadecyl)oxy]methyl]-1,3-
propanediyl ester
------------------------------------------------------------------------------
28777-98-2 2,5-Furandione, dihydro-3-(octadecenyl)- ..................................
------------------------------------------------------------------------------
28908-00-1 Benzothiazole, 2-[(chloromethyl)thio]- ..................................
------------------------------------------------------------------------------
30574-97-1 2-Butenenitrile, 2-methyl-, (2E)- ..................................
------------------------------------------------------------------------------
32072-96-1 2,5-Furandione, 3-(hexadecenyl)dihydro- ..................................
------------------------------------------------------------------------------
33509-43-2 1,2,4-Triazin-5(2H)-one, 4-amino-6-(1,1- ..................................
dimethylethyl)-3,4-dihydro-3-thioxo-
------------------------------------------------------------------------------
34689-46-8 Phenol, methyl-, sodium salt ..................................
------------------------------------------------------------------------------
35203-06-6 Benzenamine, 2-ethyl-6-methyl-N- ..................................
methylene-
------------------------------------------------------------------------------
35203-08-8 Benzenamine, 2,6-diethyl-N-methylene- ..................................
------------------------------------------------------------------------------
37439-34-2 2(1H)-Pyridinone, 3,5,6-trichloro-, ..................................
sodium salt
------------------------------------------------------------------------------
37734-45-5 Carbonochloridothioic acid, S- ..................................
(phenylmethyl) ester
------------------------------------------------------------------------------
37764-25-3 Acetamide, 2,2-dichloro-N,N-di-2- ..................................
propenyl-
------------------------------------------------------------------------------
38185-06-7 Benzenesulfonic acid, 4-chloro-3,5- ..................................
dinitro-, potassium salt
------------------------------------------------------------------------------
38321-18-5 Ethanol, 2-(2-butoxyethoxy)-, sodium ..................................
salt
------------------------------------------------------------------------------
39515-51-0 Benzaldehyde, 3-phenoxy- 6/30/1998
------------------------------------------------------------------------------
40630-63-5 1-Octanesulfonyl fluoride ..................................
------------------------------------------------------------------------------
40876-98-0 Butanedioic acid, oxo-, diethyl ester, ..................................
ion(1-), sodium
------------------------------------------------------------------------------
51632-16-7 Benzene, 1-(bromomethyl)-3-phenoxy- 6/30/1998
------------------------------------------------------------------------------
52184-19-7 Phenol, 2,4-bis(1,1-dimethylpropyl)-6- ..................................
[(2- nitrophenyl)azo]-
------------------------------------------------------------------------------
52556-42-0 1-Propanesulfonic acid, 2-hydroxy-3-(2- ..................................
propenyloxy)-, monosodium salt
------------------------------------------------------------------------------
52663-57-7 Ethanol, 2-butoxy-, sodium salt ..................................
------------------------------------------------------------------------------
[[Page 7375]]
56038-89-2 Benzenamine, N-(1-ethylpropyl)-3,5- ..................................
dimethyl-
------------------------------------------------------------------------------
56803-37-3 Phosphoric acid, (1,1- 10/4/1992
dimethylethyl)phenyl diphenyl ester
------------------------------------------------------------------------------
57693-14-8 Chromate(3-), bis[3-(hydroxy-.kappa.O)-4- ..................................
[[2-(hydroxy-.kappa.O)-1-
naphthalenyl]azo-.kappa.N1]-7-nitro-1-
naphthalenesulfonato(3-)]-, trisodium
------------------------------------------------------------------------------
61788-76-9 Alkanes, chloro ..................................
------------------------------------------------------------------------------
61789-32-0 Fatty acids, coco, 2-sulfoethyl esters, ..................................
sodium salts
------------------------------------------------------------------------------
61789-85-3 Sulfonic acids, petroleum ..................................
------------------------------------------------------------------------------
63302-49-8 Phosphorochloridous acid, bis(4- ..................................
nonylphenyl) ester
------------------------------------------------------------------------------
64742-24-1 Sludges (petroleum), acid ..................................
------------------------------------------------------------------------------
64743-02-8 Alkenes, C>10 .alpha.- ..................................
------------------------------------------------------------------------------
64743-03-9 Phenols (petroleum) ..................................
------------------------------------------------------------------------------
64771-71-7 Paraffins (petroleum), normal C>10 ..................................
------------------------------------------------------------------------------
65996-79-4 Solvent naphtha (coal) ..................................
------------------------------------------------------------------------------
65996-80-7 Ammonia liquor (coal) ..................................
------------------------------------------------------------------------------
65996-81-8 Fuel gases, coke-oven ..................................
------------------------------------------------------------------------------
65996-82-9 Tar oils, coal ..................................
------------------------------------------------------------------------------
65996-83-0 Extracts, coal tar oil alk. ..................................
------------------------------------------------------------------------------
65996-86-3 Extract oils (coal), tar base ..................................
------------------------------------------------------------------------------
65996-87-4 Extract residues (coal), tar oil alk. ..................................
------------------------------------------------------------------------------
65996-89-6 Tar, coal, high-temp. ..................................
------------------------------------------------------------------------------
65996-91-0 Distillates (coal tar), upper ..................................
------------------------------------------------------------------------------
65996-92-1 Distillates (coal tar) ..................................
------------------------------------------------------------------------------
66071-94-1 Corn, steep liquor ..................................
------------------------------------------------------------------------------
68081-86-7 Phenol, nonyl derivs. ..................................
------------------------------------------------------------------------------
68082-78-0 Lard, oil, Me esters ..................................
------------------------------------------------------------------------------
68153-60-6 Fatty acids, tall-oil, reaction products ..................................
with diethylenetriamine, acetates
------------------------------------------------------------------------------
68187-41-7 Phosphorodithioic acid, O,O-di-C1-14- ..................................
alkyl esters
------------------------------------------------------------------------------
68187-57-5 Pitch, coal tar-petroleum ..................................
------------------------------------------------------------------------------
68187-59-7 Coal, anthracite, calcined ..................................
------------------------------------------------------------------------------
68188-18-1 Paraffin oils, chlorosulfonated, ..................................
saponified
------------------------------------------------------------------------------
68308-74-7 Amides, tall-oil fatty, N,N-di-Me ..................................
------------------------------------------------------------------------------
68309-16-0 Fatty acids, tall-oil, 2-(2- ..................................
hydroxyethoxy)ethyl esters
------------------------------------------------------------------------------
68309-27-3 Fatty acids, tall-oil, sulfonated, ..................................
sodium salts
------------------------------------------------------------------------------
68334-01-0 Disulfides, alkylaryl dialkyl diaryl, ..................................
petroleum refinery spent caustic oxidn.
products
------------------------------------------------------------------------------
68441-66-7 Decanoic acid, mixed esters with ..................................
dipentaerythritol, octanoic acid and
valeric acid
------------------------------------------------------------------------------
[[Page 7376]]
68442-60-4 Acetaldehyde, reaction products with ..................................
formaldehyde, by-products from
------------------------------------------------------------------------------
68442-77-3 2-Butenediamide, (2E)-, N,N'-bis[2-(4,5- ..................................
dihydro-2-nortall-oil alkyl-1H-imidazol-
1-yl)ethyl] derivs.
------------------------------------------------------------------------------
68476-80-2 Fats and Glyceridic oils, vegetable, ..................................
deodorizer distillates
------------------------------------------------------------------------------
68478-20-6 Residues (petroleum), steam-cracked ..................................
petroleum distillates cyclopentadiene
conc., C4-cyclopentadiene-free
------------------------------------------------------------------------------
68512-63-0 Benzene, ethenyl-, distn. residues ..................................
------------------------------------------------------------------------------
68513-62-2 Disulfides, C5-12-alkyl ..................................
------------------------------------------------------------------------------
68514-41-0 Ketones, C12-branched ..................................
------------------------------------------------------------------------------
68515-89-9 Barium, carbonate nonylphenol complexes ..................................
------------------------------------------------------------------------------
68584-25-8 Benzenesulfonic acid, C10-16-alkyl ..................................
derivs., compds. with triethanolamine
------------------------------------------------------------------------------
68602-81-3 Distillates, hydrocarbon resin prodn. ..................................
higher boiling
------------------------------------------------------------------------------
68603-84-9 Carboxylic acids, C5-9 ..................................
------------------------------------------------------------------------------
68608-59-3 Ethane, 1,2-dichloro-, manuf. of, by- ..................................
products from, distn. lights
------------------------------------------------------------------------------
68609-05-2 Cyclohexane, oxidized, non-acidic by- ..................................
products, distn. lights
------------------------------------------------------------------------------
68610-90-2 2-Butenedioic acid (2E)-, di-C8-18-alkyl ..................................
esters
------------------------------------------------------------------------------
68649-42-3 Phosphorodithioic acid, O,O-di-C1-14- ..................................
alkyl esters
------------------------------------------------------------------------------
68650-36-2 Aromatic hydrocarbons, C8, o-xylene-lean ..................................
------------------------------------------------------------------------------
68782-97-8 Distillates (petroleum), hydrofined ..................................
lubricating-oil
------------------------------------------------------------------------------
68815-50-9 Octadecanoic acid, reaction products ..................................
with 2-[(2-aminoethyl)amino]ethanol
------------------------------------------------------------------------------
68909-77-3 Ethanol, 2,2'-oxybis-, reaction products ..................................
with ammonia, morpholine derivs.
residues
------------------------------------------------------------------------------
68915-05-9 Fatty acids, tall-oil, low-boiling, ..................................
reaction products with ammonia-
ethanolamine reaction by-products
------------------------------------------------------------------------------
68915-39-9 Cyclohexane, oxidized, aq. ext., sodium ..................................
salt
------------------------------------------------------------------------------
68918-16-1 Tar, coal, dried and oxidized ..................................
------------------------------------------------------------------------------
68919-17-5 Hydrocarbons, C12-20, catalytic ..................................
alkylation by-products
------------------------------------------------------------------------------
68920-64-9 Disulfides, di-C1-2-alkyl ..................................
------------------------------------------------------------------------------
68937-29-1 1,6-Hexanediol, distn. residues ..................................
------------------------------------------------------------------------------
68937-69-9 Carboxylic acids, C6-18 and C5-15-di- ..................................
------------------------------------------------------------------------------
68937-70-2 Carboxylic acids, C6-18 and C8-15-di- ..................................
------------------------------------------------------------------------------
68937-72-4 Carboxylic acids, di-, C4-11 ..................................
------------------------------------------------------------------------------
68953-70-8 Oxirane, reaction products with ammonia, ..................................
distn. residues
------------------------------------------------------------------------------
68953-80-0 Benzene, mixed with toluene, ..................................
dealkylation product
------------------------------------------------------------------------------
68955-37-3 Acid chlorides, tallow, hydrogenated ..................................
------------------------------------------------------------------------------
68955-76-0 Aromatic hydrocarbons, C9-16, biphenyl ..................................
deriv.-rich
------------------------------------------------------------------------------
68955-96-4 Disulfides, dialkyl and di-Ph, naphtha ..................................
sweetening
------------------------------------------------------------------------------
[[Page 7377]]
68987-41-7 Benzene, ethylenated ..................................
------------------------------------------------------------------------------
68987-66-6 Ethene, hydrated, by-products from ..................................
------------------------------------------------------------------------------
68988-22-7 1,4-Benzenedicarboxylic acid, dimethyl ..................................
ester, manuf. of, by-products from
------------------------------------------------------------------------------
68988-99-8 Phenols, sodium salts, mixed with sulfur ..................................
compounds, gasoline alk. scrubber
residues
------------------------------------------------------------------------------
68990-61-4 Tar, coal, high-temp., high-solids ..................................
------------------------------------------------------------------------------
68990-65-8 Fats and Glyceridic oils, vegetable, ..................................
reclaimed
------------------------------------------------------------------------------
70024-67-8 Benzenesulfonic acid, C16-24-alkyl ..................................
derives.
------------------------------------------------------------------------------
70084-98-9 Terpenes and Terpenoids, C10-30, distn. ..................................
residues
------------------------------------------------------------------------------
70693-50-4 Phenol, 2,4-bis(1-methyl-1-phenylethyl)- ..................................
6-[(2- nitrophenyl)azo]-
------------------------------------------------------------------------------
70851-08-0 Amides, coco, N-[3- ..................................
(dimethylamino)propyl], alkylation
products with sodium 3-chloro-2-
hydroxypropanesulfonate
------------------------------------------------------------------------------
71077-05-9 Ethanol, 2,2'-oxybis-, reaction products ..................................
with ammonia, morpholine product tower
residues
------------------------------------------------------------------------------
72162-28-8 2-Propanone, reaction products with ..................................
phenol
------------------------------------------------------------------------------
72854-27-4 Tannins, reaction products with sodium ..................................
bisulfite, sodium polysulfide and
sodium sulfite
------------------------------------------------------------------------------
73665-18-6 Extract residues (coal), tar oil alk., ..................................
naphthalene distn. residues
------------------------------------------------------------------------------
83864-02-2 Nickel, bis[(cyano-C)triphenylborato(1-)- ..................................
N]bis(hexanedinitrile-N,N')-
------------------------------------------------------------------------------
84501-86-0 Hexanedioic acid, esters with high- ..................................
boiling C6-10-alkene hydroformylation
products
------------------------------------------------------------------------------
90640-80-5 Anthracene oil ..................................
------------------------------------------------------------------------------
90640-86-1 Distillates (coal tar), heavy oils ..................................
------------------------------------------------------------------------------
119345-02-7 Benzene, 1,1'-oxybis-, tetrapropylene ..................................
derivs.
------------------------------------------------------------------------------
125997-20-8 Phosphoric acid, mixed 3-bromo-2,2- ..................................
dimethylpropyl and 2-bromoethyl and 2-
chloroethyl esters
----------------------------------------------------------------------------------------------------------------
[FR Doc. 05-2714 Filed 2-10-05; 8:45 am]
BILLING CODE 6560-50-S