[Federal Register Volume 70, Number 205 (Tuesday, October 25, 2005)]
[Notices]
[Pages 61622-61623]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 05-21254]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Toxic Substances and Disease Registry
[ATSDR-214]
Availability of Draft Toxicological Profiles
AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),
Department of Health and Human Services (HHS).
ACTION: Notice of availability.
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SUMMARY: The Comprehensive Environmental Response, Compensation, and
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments
and Reauthorization Act of 1986 (SARA), Section 104(i)(3) [42 U.S.C.
9604(i)(3)] directs the Administrator of ATSDR to prepare toxicological
profiles of priority hazardous substances and to revise and publish
each updated toxicological profile as necessary. This notice announces
the availability of the 19th set of toxicological profiles, which
consists of one new draft and seven updated drafts, prepared by ATSDR
for review and comment.
DATES: In order to be considered, comments on these draft toxicological
profiles must be received on or before February 27, 2006. Comments
received after the close of the public comment period will be
considered at the discretion of ATSDR on the basis of what is deemed to
be in the best interest of the general public.
ADDRESSES: Requests for printed copies of the draft toxicological
profiles should be sent to the attention of Ms. Olga Dawkins, Division
of Toxicology and Environmental Medicine, Agency for Toxic Substances
and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta,
Georgia 30333. Electronic access to these documents is also available
at the ATSDR Web site: http://www.atsdr.cdc.gov/toxpro2.html.
Comments regarding the draft toxicological profiles should be sent
to the attention of Ms. Nickolette Roney, Division of Toxicology and
Environmental Medicine, Agency for Toxic Substances and Disease
Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, Georgia
30333.
Requests for printed copies of the draft toxicological profiles
must be in writing, and must specifically identify the hazardous
substance(s) profile(s) that you wish to receive. ATSDR reserves the
right to provide only one copy of each profile requested, free of
charge. In case of extended distribution delays, requestors will be
notified.
Written comments and other data submitted in response to this
notice and the draft toxicological profiles should bear the docket
control number ATSDR-214. Send one copy of all comments and three
copies of all supporting documents to Ms. Roney at the above stated
address by the end of the comment period. Because all public comments
regarding ATSDR toxicological profiles are available for public
inspection, no confidential business information or other confidential
information should be submitted in response to this notice.
FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of
Toxicology and Environmental Medicine, Agency for Toxic Substances and
Disease Registry, Mailstop E-29, 1600 Clifton
[[Page 61623]]
Road, NE., Atlanta, Georgia 30333, telephone 1-(888)422-8737 or
(770)488-3315.
SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental
Response, Compensation, and Liability Act (CERCLA or Superfund) (42
U.S.C. 9601 et seq.) by establishing certain responsibilities for the
ATSDR and the U.S. Environmental Protection Agency (EPA) with regard to
hazardous substances which are most commonly found at facilities on the
CERCLA National Priorities List (NPL). Among these responsibilities is
that the Administrator of ATSDR prepare toxicological profiles for
substances included on the priority lists of hazardous substances.
These lists identified 275 hazardous substances that ATSDR and EPA
determined pose the most significant potential threat to human health.
The availability of the revised priority list of 275 hazardous
substances was announced in the Federal Register on November 7, 2003
(68 FR 63098). For prior versions of the list of substances see Federal
Register notices dated April 17, 1987 (52 FR 12866); October 20, 1988
(53 FR 41280); October 26, 1989 (54 FR 43619); October 17, 1990 (55 FR
42067); October 17, 1991 (56 FR 52166); October 28, 1992 (57 FR 48801);
February 28, 1994 (59 FR 9486); April 29, 1996 (61 FR 18744); November
17, 1997 (62 FR 61332); October 21, 1999 (64 FR 56792) and October 25,
2001 (66 FR 54014). [CERCLA also requires ATSDR to assure the
initiation of a research program to fill data needs associated with the
substances.] Section 104(i)(3) of CERCLA [42 U.S.C. 9604(i)(3)]
outlines the content of these profiles. Each profile will include an
examination, summary and interpretation of available toxicological
information and epidemiologic evaluations. This information and these
data are to be used to identify the levels of significant human
exposure for the substance and the associated health effects. The
profiles must also include a determination of whether adequate
information on the health effects of each substance is available or in
the process of development. When adequate information is not available,
ATSDR, in cooperation with the National Toxicology Program (NTP), is
required to assure the initiation of research to determine these health
effects.
Although key studies for each of the substances were considered
during the profile development process, this Federal Register notice
seeks to solicit any additional studies, particularly unpublished
data and ongoing studies, which will be evaluated for possible
addition to the profiles now or in the future.
The following draft toxicological profiles will be made available
to the public on or about October 17, 2005.
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Document Hazardous substance CAS No.
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1................................ ACROLEIN (Update).. 000107-02-8
2................................ ARSENIC (Update)... 007440-38-2
3................................ BARIUM (Update).... 007440-39-3
4................................ BENZENE (Update)... 000071-43-2
5................................ HEPTACHLOR (Update)/ 000076-44-8
.
HEPTACHLOR EPOXIDE. 001024-57-3
6................................ LEAD (Update)...... 007439-92-1
7................................ PERCHLORATES *..... 014797-73-0
8................................ XYLENES (Update)... 001330-20-7
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* Denotes new profile.
All profiles issued as ``Drafts for Public Comment'' represent
ATSDR's best efforts to provide important toxicological information on
priority hazardous substances. We are seeking public comments and
additional information which may be used to supplement these profiles.
ATSDR remains committed to providing a public comment period for these
documents as a means to best serve public health and our clients.
Dated: October 17, 2005.
Ken Rose,
Acting Director, Office of Policy, Planning and Evaluation, National
Center for Environmental Health/Agency for Toxic Substances and Disease
Registry.
[FR Doc. 05-21254 Filed 10-24-05; 8:45 am]
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