[Federal Register Volume 75, Number 90 (Tuesday, May 11, 2010)]
[Notices]
[Pages 26257-26258]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-11180]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30Day-10-09BQ]
Agency Forms Undergoing Paperwork Reduction Act Review
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail
to [email protected]. Send written comments to CDC Desk Officer, Office of
Management and Budget, Washington, DC or by fax to (202) 395-5806.
Written comments should be received within 30 days of this notice.
Proposed Project
Examining In-vehicle Exposures to Air Pollutants and Corresponding
Health Outcomes of Commuters--New--National Center for Environmental
Health, (NCEH) and Agency for Toxic Substances and Disease Registry
(ATSDR), Centers for Disease Control and Prevention, (CDC).
Background and Brief Description
Numerous studies have found associations between ambient fine
particulate matter (PM2.5) and adverse cardiovascular
outcomes. Several recent epidemiologic studies suggest that vehicle-
related emissions, in particular, may be linked to many of the these
adverse effects and that specific sub-populations may be more
susceptible to health risks due to their enhanced exposures to vehicle-
related PM2.5 sources. Commuters are a potentially
susceptible, yet poorly characterized, sub-population. Importantly,
recent epidemiologic studies indicate that specific sub-groups,
including those with asthma, may be at risk to cardio respiratory
health effects due to their pre-existing health condition. A more
complete understanding of in-vehicle exposures for the commuter
population, especially those with asthma, is therefore becoming
increasingly necessary as commuting durations and roadway congestion
have steadily increased throughout the U.S. during the last 20 years.
The National Center for Environmental Health (NCEH), Centers for
Disease Control and Prevention (CDC) will conduct this study to
characterize in-vehicle exposures to traffic-related air pollutants
among commuters, with and without asthma, and any health impacts that
these exposures may have on the commuter.
A total of 40 participants (20 adults with physician-diagnosed
asthma and 20 healthy adults) living in the Atlanta metro area will be
recruited for participation in this study. Participants will be
excluded if they meet specific criteria including: ever being diagnosed
with severe asthma, ever suffering a myocardial infarction, smoking
tobacco products, or ever being diagnosed with a pulmonary disease such
as emphysema, chronic obstructive pulmonary disorder (COPD), or any
type of lung cancer, will be excluded.
Prior to their scheduled commute, participants will complete a one-
time baseline questionnaire to assess medical history and general
exposures. Additionally, a short symptom diary recording any
respiratory symptoms will be completed by the participant prior to the
commute and health measurements for lung function, lung inflammatory
markers, heart rate, and biomarkers of systemic inflammation will be
conducted by a trained field technician. In-vehicle exposures to
particulate matter and other air pollutants will then be measured for
all participants during their commute. After the commute, the symptom
diary and health measurements will be conducted again to assess any
potential changes in respiratory and cardiovascular health effects.
Each participant will conduct the commute two times during the study
year. The information learned from the health measurements and diary
entries before and after the commute will be important in better
understanding the potential acute health impacts associated with
exposures to in-vehicle traffic pollutants and respiratory and
cardiovascular health, and whether urban commuters--especially those
with asthma--should be viewed as a susceptible sub-population given
their enhanced exposures to PM2.5 and gas-phase pollutants.
There is no cost to participants other than their time. The
estimated annual burden hours are 180 hours.
[[Page 26258]]
Estimated Annualized Burden Hours
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Average
No. of No. of burden per
Respondents Instrument type respondents responses per respondent (in
respondent hours)
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Eligible participants.............. Baseline questionnaire..... 40 1 20/60
Symptom survey............. 40 5 2/60
Scripted commute data 40 2 2
collection.
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Dated: May 5, 2010.
Maryam I. Daneshvar,
Reports Clearance Officer, Centers for Disease Control and Prevention.
[FR Doc. 2010-11180 Filed 5-10-10; 8:45 am]
BILLING CODE 4163-18-P